Evidence map›Paper›PMID 42442501›Full record

ArticleThe Journal of biological chemistry2026

The structure of the SufBC

Nidhi Chhikara, Nadia Mireku, Jack A Dunkle, Patrick A Frantom

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Nidhi ChhikaraDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Nadia MirekuDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA.
Jack A DunkleDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA. Electronic address: jadunkle@ua.edu.
Patrick A FrantomDepartment of Chemistry & Biochemistry, The University of Alabama, Tuscaloosa, Alabama, USA. Electronic address: pfrantom@ua.edu.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Conformational dynamics and allosteric regulation during stress-responsive metallocofactor assemblyR01GM112919 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI Patrick Frantom · 2015 to 2026
$2.8M
Acquisition of cryo-electron microscopeS10OD024978 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DOKLAND, TERJE · 2020 to 2020
$2.0M
Determining the specificity and regulation of Type III CRISPR-Cas interferenceR35GM142966 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI DUNKLE, JACK ALBERT · 2021 to 2025
$1.8M
NCI NIH HHS P30 CA013148NIGMS NIH HHS R01 GM112919NIGMS NIH HHS R35 GM142966NIH HHS S10 OD024978
6 · The paper itself

Abstract

Iron-sulfur clusters are essential cofactors assembled in bacteria by the Suf pathway through a series of transient protein-protein interactions that transfer sulfur from L-cysteine to a scaffold complex. While early steps in persulfide transfer are well-characterized, the mechanism of sulfur delivery to the SufBC

Indexed as

Escherichia coli ProteinsIron-Sulfur ProteinsSulfurCarrier ProteinsCrystallography, X-RayModels, MolecularProtein ConformationSulfidesCarrier ProteinsEscherichia coli ProteinsIron-Sulfur ProteinsSufB protein, E coliSulfidesSulfurFe-S cluster assemblypersulfide transferSufBC(2)DSufEsuf pathway

Identifiers

PMID42442501
PMCPMC13485665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.