Evidence map›Paper›PMID 42441561›Full record

ArticlePLOS mental health2026

The psychosocial impact of disability and stigma among persons affected by leprosy and lymphatic filariasis in India.

Robin van Wijk, Ashok Agarwal, Pradeepta Nayak, Chandra Pati Mishra, Sneha Toppo, Rohit K Tiwari, Pravin Kumar, Amit Jain, Marente M Mol, Arup K Chakrabartty and 3 more

Abstract read
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Article in PLOS mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Robin van WijkNLR | Until No Leprosy Remains, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-0969-4155
Ashok AgarwalNLR India Foundation, New Delhi, India.
Pradeepta NayakNLR India Foundation, New Delhi, India.
Chandra Pati MishraDepartment of Community Medicine, Heritage Institute of Medical Sciences, Varanasi, India.ORCID https://orcid.org/0000-0001-5691-5101
Sneha ToppoNLR India Foundation, New Delhi, India.
Rohit K TiwariNLR India Foundation, New Delhi, India.
Pravin KumarNLR India Foundation, New Delhi, India.
Amit JainNLR India Foundation, New Delhi, India.
Marente M MolNLR | Until No Leprosy Remains, Amsterdam, The Netherlands.
Arup K ChakrabarttyNLR India Foundation, New Delhi, India.
Jan Hendrik RichardusDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-0564-6313
Ida J KorfageDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Wim van BrakelNLR | Until No Leprosy Remains, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neglected tropical diseases (NTDs), such as leprosy and lymphatic filariasis (LF), can cause disabilities despite available treatment. Both diseases disproportionately affect India's poorest populations, with high numbers in Jharkhand and Uttar Pradesh. Those affected experience severe psychosocial consequences, including participation restrictions, depression, and poor mental health. This study investigates the extent to which stigma affects social participation and mental wellbeing among persons with leprosy- and LF-related disabilities in two Indian states. In a cross-sectional design in Bokaro (Jharkhand) and Jaunpur (Uttar Pradesh), participants were randomly selected among persons with leprosy- or LF-related disabilities, along with comparable non-affected community members. Sociodemographic and disability data were collected, alongside four measures assessing mental wellbeing, depression, participation restriction, and stigma. Analysis used descriptive statistics, univariate, and multivariate regression. A total of 201 persons with leprosy-related disabilities, 240 with LF-related disabilities, and 98 non-affected community members were included. Persons with NTD-related disabilities exhibited significantly higher depression and participation restriction and reported lower mental wellbeing compared to community members (p < 0.001). In the leprosy group, lower education and lower stigma were key determinants of mental wellbeing (R² = 0.3), while in the LF group, higher age and less severe lymphoedema grade were significant (R² = 0.5). Participation restriction was associated with higher age, poorer mental wellbeing, and depression in the leprosy group (R² = 0.7), and with depression and stigma in the LF group (R² = 0.6). Persons with leprosy and LF-related disabilities face significant psychosocial challenges, including poor mental wellbeing, depression, and restrictions in participation, often exacerbated by stigma. Addressing these challenges requires integration of mental health support and stigma reduction within NTD programmes, with specific attention to the needs of persons with disabilities. Further research into connections between education, disability, and mental health is essential to deepen understanding and inform development of more targeted, effective interventions.

Identifiers

PMID42441561
PMCPMC13362095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.