Evidence map›Paper›PMID 42441528›Full record

ArticleMolecular nutrition & food research2026

PPAR

Mónica Sánchez-Tapia, Sandra Tobón-Cornejo, Martha Guevara-Cruz, Laura A Velázquez-Villegas, Rogelio Hernández-Pando, Adriana López-Barradas, Rocio Guizar-Heredia, Otoniel Maya, Janette Furuzawa-Carballeda, Rosa Rebollar-Vega and 3 more

Abstract read
In one paragraph

Article in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mónica Sánchez-TapiaDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Sandra Tobón-CornejoDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Martha Guevara-CruzDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Laura A Velázquez-VillegasDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Rogelio Hernández-PandoDepartamento De Patología Experimental, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Adriana López-BarradasDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Rocio Guizar-HerediaDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Otoniel MayaPhysics Department, Chalmers University of Technology, Gothenburg, Sweden.
Janette Furuzawa-CarballedaDepartamento de Cirugía Experimental, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Rosa Rebollar-VegaRED de apoyo a la investigación, Coordinación de la Investigación Científica, UNAM e Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Ariana Vargas-CastilloDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Nimbe TorresDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.
Armando R TovarDepartamento De Fisiología de La Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.

Funding

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán 256552-M
6 · The paper itself

Abstract

The peroxisome proliferator-activated receptor alpha (PPARα) is a key regulator of lipid metabolism and energy homeostasis. However, its role in shaping the gut microbiota requires further investigation. Therefore, the aim of the present study was to investigate whether the lack of PPARα in a mouse model or the presence of a single nucleotide polymorphism (SNP) rs6008259 of PPARα in humans can modulate the gut microbiota and its association with metabolic alterations. PPARα

Indexed as

Gastrointestinal MicrobiomePPAR alphaAdultAnimalsBody CompositionFemaleHomeostasisHumansLiverMaleMiceMice, Inbred C57BLMice, KnockoutPolymorphism, Single NucleotideTriglyceridesPPAR alphaPpara protein, mouseTriglyceridescolonic hypoxiagut microbiotaPPARαSNP rs6008259triglycerides

Identifiers

PMID42441528
PMCPMC13362006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.