Evidence map›Paper›PMID 42441269›Full record

ArticleMaterials today. Bio2026

Translational hydrogel platform for durable sealing and mechanical restoration of annular defects.

Zijie Zhang, Dan Zhou, Wantao Wang, Lingtian Lu, Jian Zhu, Yiwen Xian, Yixi Li, William Weijia Lu, Zhaomin Zheng, Hongmei Liu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zijie ZhangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Dan ZhouGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Wantao WangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Lingtian LuGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Jian ZhuGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Yiwen XianGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Yixi LiGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
William Weijia LuDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, 999077, Hong Kong, China.
Zhaomin ZhengDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
Hongmei LiuGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.
Decheng WuGuangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional discectomy surgery for treating intervertebral disc (IVD) herniation remains limited in addressing post-surgery annulus fibrosus (AF) injury, resulting in high reoccurrence rate. However, repair of AF defects following discectomy remains challenging due to the complex biomechanics and anatomy of the IVD, as well as the mechanical limitations of biomaterials, which often fails to provide sufficient mechanical integration, durable tissue adhesion, and long-term biocompatibility. To address these unmet clinical challenges, we developed an adhesive hydrogel scaffold (AHS) composed of a chitosan-based fibrous hydrogels mechanical patch (FH

Indexed as

Annulus fibrosus defect repairBioadhesivePost-discectomy repairTissue engineering

Identifiers

PMID42441269
PMCPMC13334823

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.