Evidence map›Paper›PMID 42441251›Full record

ArticleChemical science2026

HFGuidedDesign:

Haomeng Hu, Renjie Zhu, Ning Zhu, Chengyun Zhang, Tianfeng Shang, Chongyang Li, Jingjing Guo, Xudong Wang, Hongliang Duan

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haomeng HuCollege of Pharmaceutical Sciences, Zhejiang University of Technology Hangzhou 310014 China xdwang2019@zjut.edu.cn.ORCID https://orcid.org/0009-0008-1579-2983
Renjie ZhuCollege of Pharmaceutical Sciences, Zhejiang University of Technology Hangzhou 310014 China xdwang2019@zjut.edu.cn.
Ning ZhuFaculty of Applied Sciences, Macao Polytechnic University Macao 999078 China hduan@mpu.edu.mo.
Chengyun ZhangFaculty of Applied Sciences, Macao Polytechnic University Macao 999078 China hduan@mpu.edu.mo.ORCID https://orcid.org/0000-0002-8499-5273
Tianfeng ShangAI Department, Shenzhen Highslab Therapeutics. Inc Shenzhen 518000 China.
Chongyang LiFaculty of Applied Sciences, Macao Polytechnic University Macao 999078 China hduan@mpu.edu.mo.
Jingjing GuoFaculty of Applied Sciences, Macao Polytechnic University Macao 999078 China hduan@mpu.edu.mo.ORCID https://orcid.org/0000-0002-4632-4364
Xudong WangCollege of Pharmaceutical Sciences, Zhejiang University of Technology Hangzhou 310014 China xdwang2019@zjut.edu.cn.ORCID https://orcid.org/0000-0003-2700-1399
Hongliang DuanFaculty of Applied Sciences, Macao Polytechnic University Macao 999078 China hduan@mpu.edu.mo.ORCID https://orcid.org/0000-0002-9194-0115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic peptides are promising scaffolds for targeting protein surfaces due to their unique structural and functional advantages. However, the limited availability of cyclic peptide-protein complex structures severely restricts the design of target-specific cyclic peptides. Here, we introduce HFGuidedDesign, a

Identifiers

PMID42441251
PMCPMC13334703

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.