Evidence map›Paper›PMID 42441231›Full record

ArticleJournal of neuroendovascular therapy2026

Transarterial Embolization for Medically Refractory Kasabach-Merritt Syndrome: A Case Report.

Taiga Matsumoto, Hiro Kiyosue, Yasuyuki Kaku, Hidetaka Hayashi, Yoshitaka Tamura, Akitake Mukasa, Toshinori Hirai

Abstract readCase Reports
In one paragraph

Article in Journal of neuroendovascular therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taiga MatsumotoDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Hiro KiyosueDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Yasuyuki KakuDepartment of Neurosurgery, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Hidetaka HayashiDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Yoshitaka TamuraDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Akitake MukasaDepartment of Neurosurgery, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.
Toshinori HiraiDepartment of Diagnostic Radiology, Kumamoto University Hospital, Kumamoto, Kumamoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Kasabach-Merritt syndrome (KMS) is a life-threatening disorder characterized by severe thrombocytopenia and consumptive coagulopathy associated with vascular tumors, typically Kaposiform hemangioendothelioma (KHE) or tufted angioma. Drug therapy is the first-line treatment, but some cases are refractory, and no established salvage therapy exists. This report describes a case of KMS resistant to multiple drug therapies in which transarterial embolization (TAE) was successfully performed. Case Presentation: A 2-month-old male infant presented with a left posterior neck mass. Examination revealed severe thrombocytopenia (5000/μL) and coagulation abnormalities. Imaging studies diagnosed KMS with KHE. Platelet counts did not improve despite sequential treatment with corticosteroids, beta-blockers, and sirolimus. TAE was indicated due to the high risk of fatal bleeding. Angiography identified feeding vessels from the posterior muscular branch of the vertebral artery and the ascending cervical artery. TAE was performed using 20% n-butyl-2-cyanoacrylate (NBCA) for the vertebral artery branch and gelatin sponge particles for the ascending cervical artery branch. Post-embolization, platelet counts normalized, and the tumor shrank. Conclusion: In a case of drug-resistant KMS, TAE effectively restored platelet counts and prevented fatal complications. When performed with appropriate embolic selection and careful complication management, arterial embolization can be a useful adjunctive treatment.

Indexed as

infantKaposiform hemangioendotheliomaKasabach–Merritt syndromen-butyl-2-cyanoacrylate (NBCA)transarterial embolization

Identifiers

PMID42441231
PMCPMC13337326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.