Evidence map›Paper›PMID 42441216›Full record

ReviewIndian journal of dermatology

A Comprehensive Overview on Alopecia Areata with Review on Advances in Genetics and Treatment.

Sudip Das, Apeksha Singh, Sk Shahriar Ahmed

Abstract readReview
In one paragraph

Review in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sudip DasFrom the Department of Dermatology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.
Apeksha SinghFrom the Department of Dermatology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.
Sk Shahriar AhmedDepartment of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia areata (AA) is a chronic autoimmune disorder characterised by sudden, non-scarring hair loss due to the immune system mistakenly attacking hair follicles. It affects approximately 2% of the population and can manifest in various patterns, ranging from small patches to total loss of scalp and body hair. While the exact cause remains unknown, genetic predisposition and environmental triggers play a significant role in its development. Hair follicles in affected individuals become arrested in later stages of the hair growth cycle, leading to premature transition to the catagen or telogen phase and impaired regrowth. Though not life-threatening, AA has profound psychological and emotional effects, impacting self-esteem and quality of life. Various treatment options, including corticosteroids, immunotherapy, and emerging biologic therapies, aim to manage symptoms and promote hair regrowth, but no definitive cure exists. Ongoing research continues to explore the genetic and immunological mechanisms underlying the condition to develop more effective treatments. Awareness and support for individuals with AA remain crucial in helping them cope with the physical and emotional challenges associated with the disorder. This article provides a comprehensive overview of the genetics, causes, and treatment options for AA.

Indexed as

Alopecia areataautoimmune disorderbiologic therapiesgenetic predispositionimmune systemimmunotherapypsychological impacttreatment options

Identifiers

PMID42441216
PMCPMC13336548

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.