Evidence map›Paper›PMID 42441174›Full record

ArticleNeurophotonics2026

Understanding variability in full-term newborns' fNIRS data: the impact of birth weight and gestational age on infants' speech perception abilities.

Noémi Petra Szeberényi, Judit Gervain, Jessica Gemignani

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In one paragraph

Article in Neurophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Noémi Petra SzeberényiUniversity of Padua, Department of Developmental Psychology and Socialisation, Padua, Italy.ORCID https://orcid.org/0009-0008-8847-7810
Judit GervainUniversity of Padua, Department of Developmental Psychology and Socialisation, Padua, Italy.ORCID https://orcid.org/0000-0002-2125-6369
Jessica GemignaniUniversity of Padua, Department of Developmental Psychology and Socialisation, Padua, Italy.ORCID https://orcid.org/0000-0002-7722-4489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Language acquisition is a complex process already influenced by prenatal neural development and auditory experiences. From the onset of the third trimester, fetuses perceive sounds already influencing the fetal brain. Aim: The study investigates how the length of intrauterine language exposure, indexed by gestational age (GA), and overall maturation, indexed by birth weight (BW), affect full-term newborns' brain responses to linguistic stimuli. Approach: Data from 14 near-infrared spectroscopy studies testing responses to different auditory sound patterns in 192 0- to 7-day-old newborns were pooled together and analyzed to assess the impact of GA and BW on changes in oxygenated hemoglobin (HbO) and deoxygenated hemoglobin (HbR). Results: Results showed that, for HbO, activations in both considered conditions were larger in the temporal than in the frontal areas, irrespective of BW or GA. A similar spatial pattern was observed for HbR, with stronger responses in the temporal compared with frontal regions across conditions. In contrast, when considering effect sizes and reflecting discrimination abilities, these were more strongly associated with BW in the bilateral frontal regions, whereas in the bilateral temporal regions, they were more strongly associated with GA. Conclusions: The findings suggest a differential impact of BW and GA on neural measures of linguistic sensitivity in newborns, reflecting their roles in biological maturation and auditory experience, respectively. Overall, the study suggests that both the length of prenatal experience and maturation play significant roles in shaping newborns' hemodynamic responses.

Indexed as

hemodynamic responsenear-infrared spectroscopynewbornsperinatal physiological measuresprenatal language experience

Identifiers

PMID42441174
PMCPMC13336347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.