Evidence map›Paper›PMID 42441161›Full record

ArticleCase reports in dermatology

Primary Subcutaneous Candidiasis Presenting as a Chronic Eschar-Covered Ulcer: A Diagnostic Challenge in an Immunocompromised Host - A Case Report and Literature Review.

Kumudhavalli Kavanoor Sridhar, Greg J German, Sigmund Krajden, Zared Aziz, Yan Chen, James A Scott, Richard C Summerbell

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kumudhavalli Kavanoor SridharDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Greg J GermanDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Sigmund KrajdenDivision of Infectious Disease, Department of Medicine, Unity Health, University of Toronto, Toronto, ON, Canada.
Zared AzizDepartment of Laboratory Medicine and Pathobiology, Unity Health Toronto, Toronto, ON, Canada.
Yan ChenDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
James A ScottDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Richard C SummerbellDalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Primary subcutaneous candidiasis is a rare, severe opportunistic infection. While Case Presentation: We describe an 83-year-old male with high-risk myelodysplastic syndrome (MDS) and acute myeloid leukemia who developed a nonhealing eschar-covered ulcer on his left shin following a minor gardening injury. Despite multiple courses of broad-spectrum antibiotics, the lesion persisted. Initial superficial cultures were dismissed as colonization. However, multiple deep tissue biopsies and high-throughput internal transcribed spacer 2 sequencing confirmed invasive Conclusion: This case highlights the diagnostic challenge of "atypical" fungal ulcers. It underscores the importance of deep tissue biopsies and molecular sequencing in neutropenic patients to differentiate invasive pathogens from surface colonization and prevent systemic dissemination.

Indexed as

Acute myeloid leukemiaCandida albicansEschar-covered ulcerMyelodysplastic syndromeOpportunistic fungal infectionPrimary subcutaneous candidiasis

Identifiers

PMID42441161
PMCPMC13336724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.