Evidence map›Paper›PMID 42441100›Full record

ArticleMaterials today. Bio2026

A γ-radiation-responsive diselenide-core micelle for on-demand delivery of cannabidiol in the mitigation of acute radiation injury.

Caifeng Guo, Xin Shen, Rui Wang, Zhijie Bai, Lin Lin, Jiading Weng, Ningning Wang, Pan Shen, Lei Zhou, Shaoyun Guo and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Caifeng GuoState Key Laboratory of Advanced Polymer Materials (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu, 610065, China.
Xin ShenAcademy of Military Medical Sciences, Beijing, 100850, China.
Rui WangAcademy of Military Medical Sciences, Beijing, 100850, China.
Zhijie BaiAcademy of Military Medical Sciences, Beijing, 100850, China.
Lin LinAcademy of Military Medical Sciences, Beijing, 100850, China.
Jiading WengAcademy of Military Medical Sciences, Beijing, 100850, China.
Ningning WangAcademy of Military Medical Sciences, Beijing, 100850, China.
Pan ShenAcademy of Military Medical Sciences, Beijing, 100850, China.
Lei ZhouAcademy of Military Medical Sciences, Beijing, 100850, China.
Shaoyun GuoState Key Laboratory of Advanced Polymer Materials (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu, 610065, China.
Xianlong ZhangState Key Laboratory of Advanced Polymer Materials (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu, 610065, China.
Wei ZhouState Key Laboratory of Advanced Polymer Materials (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu, 610065, China.
Yue GaoAcademy of Military Medical Sciences, Beijing, 100850, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the widespread application of nuclear energy, the associated risks of nuclear accidents and radiation leakage have increased considerably. To address potential acute radiation injuries and reduce the toxicity burden posed by conventional radioprotective agents, the development of novel therapeutic strategies is urgently needed. In this study, we designed a γ-radiation-responsive drug delivery system by encapsulating the radioprotective agent cannabidiol (CBD) into amphiphilic polymer micelles (denoted as mPEG-SeSe-St@CBD) incorporating diselenide bonds as radiation-sensitive units. The resulting micelles exhibited a small particle size (≈155 nm), negative surface charge (zeta potential = -14.5 mV), and a stable spherical morphology.

Indexed as

Diselenide bondDrug deliveryPolymeric micellesRadiation injuryγ-irradiation

Identifiers

PMID42441100
PMCPMC13334824

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.