ArticleMedComm2026
Preoperative Albumin Infusion Reduced Pulmonary Complications in Elderly Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Single-Center, Randomized, Double-Blind, Controlled Pilot Trial.
Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Hypoalbuminemia is a recognized risk factor for postoperative pulmonary complications (PPCs), but whether preoperative albumin infusion improves pulmonary outcomes after cardiac surgery remains unclear. In this single-center, randomized, double-blind, controlled pilot trial (ChiCTR2300076609), 80 elderly patients with preoperative albumin concentrations <40 g/L who underwent elective cardiac surgery with cardiopulmonary bypass were randomly assigned to receive 100 mL of 20% albumin (40 patients) or saline before surgery (40 patients). The primary outcomes were PPC severity and incidence during hospitalization, and perioperative immune cell changes were also explored. All randomized participants completed the trial. Compared with the controls, the patients in the albumin group had lower PPC severity (median [IQR], 1 [1-2] vs. 2 [2-3]; mean difference, -0.75; 95% CI, -1.15 to -0.35;
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