Evidence map›Paper›PMID 42440970›Full record

ArticleCureus2026

Diagnostic Reclassification From Parkinson's Disease to Multiple System Atrophy Based on Longitudinal Clinical and Imaging Findings: A Case Report.

Shoji Kikui, Yoshihiro Kashiwaya, Daisuke Danno, Takao Takeshima

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shoji KikuiNeurology, Tominaga Hospital, Osaka, JPN.
Yoshihiro KashiwayaNeurology, Tominaga Hospital, Osaka, JPN.
Daisuke DannoNeurology, Tominaga Hospital, Osaka, JPN.
Takao TakeshimaNeurology, Tominaga Hospital, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is often challenging to differentiate Parkinson's disease (PD) from multiple system atrophy (MSA) - particularly, the parkinsonian subtype (MSA-P) - in the early disease stages because of overlapping clinical features. Here, we report the case of a 72-year-old man who was initially diagnosed with PD but whose diagnosis was later changed to MSA-P following the emergence of autonomic dysfunction and characteristic magnetic resonance imaging (MRI) findings. He presented with tremors, rigidity, bradykinesia, and postural instability, and dopamine transporter imaging demonstrated bilateral presynaptic dopaminergic dysfunction. Cardiac

Indexed as

123i-mibg myocardial scintigraphydiagnostic approachlongitudinal multimodal diagnostic approachmultiple system atrophy (msa)parkinson's diseaseselegiline

Identifiers

PMID42440970
PMCPMC13334789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.