Evidence map›Paper›PMID 42440823›Full record

ArticleERJ open research2026

Lung function across the life course in Kenya: a series of cross-sectional surveys.

Hellen Meme, Sophie Matu, Fred Orina, Barbara Miheso, Richard Kiplimo, Amos Ndombi, Immaculate Kathure, James Kinyanjui, Evans Amukoye, Jeragingh Chakaya and 11 more

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Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Hellen MemeCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Sophie MatuCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Fred OrinaCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Barbara MihesoCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Richard KiplimoCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Amos NdombiCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Immaculate KathureDivision of Tuberculosis and Other Lung Diseases, Ministry of Health, Nairobi, Kenya.
James KinyanjuiKenya National Bureau of Statistics, Nairobi, Kenya.
Evans AmukoyeCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Jeragingh ChakayaCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.
Nengjie HeNational Heart and Lung Institute, Imperial College, London, UK.
Cressida BowyerFaculty of Creative and Cultural Industries, University of Portsmouth, Portsmouth, UK.
Cindy M GraySchool of Social and Political Sciences, University of Glasgow, Glasgow, UK.
Maia LesoskyNational Heart and Lung Institute, Imperial College, London, UK.
Kevin MortimerCambridge Africa, Department of Pathology, University of Cambridge, Cambridge, UK.
Sean SempleInstitute for Social Marketing and Health, University of Stirling, Stirling, UK.
Sarah E WestStockholm Environment Institute, University of York, York, UK.
Lindsay ZurbaEducation for Health Africa, Durban, South Africa.
Amsalu B BinegdieDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-9722-6265
Asma El SonyEpidemiological Laboratory for Public Health, Research and Development, Khartoum, Sudan.ORCID https://orcid.org/0000-0002-6989-8862
Graham DevereuxCentre for Respiratory Disease Research, Kenya Medical Research Institute, Nairobi, Kenya.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: The high prevalence of COPD in sub-Saharan Africa is poorly understood. In high-income countries, COPD is the consequence of suboptimal lung growth during childhood and/or accelerated lung function decline in adult life. We have conducted cross-sectional studies to measure the lung function of children and adults in Kenya and to identify associations with age. Methods: We performed spirometry in three groups in Kenya: a random sample of schoolchildren in two districts of urban Nairobi and age/sex-stratified representative community samples of adults in Nairobi and rural Machakos. Forced expiratory volume in 1 s (FEV Results: The mean (95% CI) FEV Conclusion: The lung function of children and adults in Kenya was lower than predicted by race-neutral Global Lung Function Initiative (GLI)-Global reference equations. In adults, a negative association between lung function and age was greater in urban, than in rural, settings. Further work is required to identify and mitigate relevant influences.

Identifiers

PMID42440823
PMCPMC13334340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.