ArticleFrontiers in neurology
The effect of probiotic supplements on cognitive outcomes and neuroplasticity in elderly ischemic stroke survivors.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This retrospective cohort study investigates the effects of probiotic supplementation on the nutritional, cognitive, and motor functions of elderly survivors recovering from ischemic stroke. Given the high prevalence of nutritional deficits and cognitive impairments in this population, exploring adjunct therapies such as probiotics could provide improved outcomes. Methods: The study included 223 elderly ischemic stroke survivors treated between March 2021 and February 2024, divided into two groups based on treatment modalities: the Conventional Group ( Results: Baseline comparisons showed no significant differences between groups. Post-treatment outcomes demonstrated significant improvements in the Supplement Group across several measures. Neurotrophic and nutritional parameters, including BDNF, hemoglobin, albumin, and prealbumin levels, significantly increased ( Conclusion: Probiotic supplementation as part of nutritional therapy significantly enhances nutritional, cognitive, and motor function recovery in elderly ischemic stroke survivors, while also reducing gastrointestinal adverse events. These findings suggest that incorporating probiotics into recovery protocols post-stroke may facilitate better health outcomes and provide a well-tolerated therapeutic adjunct.
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