Evidence map›Paper›PMID 42440652›Full record

ArticleClinical case reports2026

Pembrolizumab-Associated Serositis With Recurrent Pleural Effusions Successfully Treated With Anakinra.

Emma McNally, Sean Garvey, Malcolm Herron, Niall Conlon, Sinead Cuffe, Richard Conway, Laura Gleeson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma McNallyRespiratory Department St James's Hospital Dublin Ireland.
Sean GarveyRespiratory Department St James's Hospital Dublin Ireland.
Malcolm HerronRespiratory Department St James's Hospital Dublin Ireland.
Niall ConlonClinical Immunology Department St James's Hospital Dublin Ireland.
Sinead CuffeMedical Oncology Department St James's Hospital Dublin Ireland.
Richard ConwayRheumatology Department St James's Hospital Dublin Ireland.
Laura GleesonRespiratory Department St James's Hospital Dublin Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitor-associated serositis is rare and may present with recurrent effusions. Some cases are steroid dependent, contributing to significant toxicity for patients. Guidance on steroid-sparing therapy is limited. Our case describes IL-1 blockade with anakinra which was well tolerated and effective, supporting its use as a steroid-sparing option.

Indexed as

anakinraimmune checkpoint inhibitorsimmune‐related adverse eventsnon‐small cell lung cancerpleural effusionsserositis

Identifiers

PMID42440652
PMCPMC13333690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.