ArticleFrontiers in microbiology2026
Phenotypic, PCR, and whole-genome sequencing characterization of carbapenem-resistant
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Carbapenem-resistant Methods: We analyzed 71 non-duplicate multidrug-resistant (MDR) Results: By BMD, carbapenem resistance was essentially universal (imipenem [IMI] 100% in both cities; meropenem [MEM] 100% in Makkah and 97.2% in Riyadh). VITEK II software showed high categorical agreement with BMD (94-100% across drug city strata) but non-zero very major error (VME) rates for carbapenems (up to 5.9%), supporting reflex BMD confirmation for decision-changing susceptible calls. The composite PCR marker ( Conclusion: A combined same-day PCR rule-in, reference MIC confirmation, and WGS micro-cluster surveillance strategy operationalizes rapid CRAB triage and outbreak triggering in hospitals in Saudi Arabia, enabling proactive infection-prevention containment.
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