Evidence map›Paper›PMID 42440388›Full record

ArticleCureus2026

A Modified Enhanced Recovery After Surgery Protocol Versus Standard Care in Pediatric Major Gastrointestinal Surgery: A Randomized Controlled Trial.

Andi Ade Wijaya Ramlan, Kshetra Rinaldhy, Rahendra Rahendra, Raihanita Zahra, Komang Ayu Ferdiana, Rizky Amaliah, Hardian Gunardi, Wulan Ayudyasari, Niken Wahyu Puspaningtyas, Christopher Kapuangan and 1 more

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andi Ade Wijaya RamlanDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Kshetra RinaldhyDepartment of Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Rahendra RahendraDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Raihanita ZahraDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Komang Ayu FerdianaDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Rizky AmaliahDepartment of Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Hardian GunardiDepartment of Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Wulan AyudyasariDepartment of Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Niken Wahyu PuspaningtyasDepartment of Child Health, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Christopher KapuanganDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.
Arif Hari Martono MarsabanDepartment of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Perioperative management in pediatric major gastrointestinal surgery often involves prolonged fasting, delayed mobilization, and invasive monitoring, which may increase stress responses and slow recovery. Enhanced recovery after surgery (ERAS) pathways are well established in adults but require pediatric adaptation. This study evaluated a modified ERAS protocol versus standard care in pediatric patients undergoing major gastrointestinal surgery. Methodology This single-blind randomized controlled trial enrolled pediatric patients aged two months to five years undergoing major gastrointestinal surgery. Participants were randomized to a modified ERAS group (n = 40) or standard care group (n = 42). Outcomes included time to first oral nutrition, time to first mobilization, time to urinary catheter removal, length of hospital stay, and intraoperative glucose and electrolyte levels. Results Early mobilization was significantly faster in the modified ERAS group (p = 0.014), and length of hospital stay was shorter (p = 0.018). The modified ERAS group demonstrated lower intraoperative glucose levels at later intraoperative timepoints (timepoint 2, p = 0.047; timepoint 3, p = 0.008). There were no significant differences in time to first oral nutrition, urinary catheter removal, or intraoperative electrolyte levels between groups. Conclusions A modified ERAS protocol in pediatric major gastrointestinal surgery was associated with earlier mobilization, shorter hospitalization, and improved intraoperative glucose stability compared with standard care. Adoption of pediatric-adapted ERAS pathways may improve perioperative outcomes in this population.

Indexed as

carbohydrate loadingearly mobilizationenhanced recovery after surgeryintraoperative glucoselength of hospital staypediatric anesthesiapediatric eras protocolpediatric gastrointestinal surgeryperioperative care pathwayrandomized controlled trial

Identifiers

PMID42440388
PMCPMC13333259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.