ArticleLa Radiologia medica2026
Diagnostic performance of abbreviated MRI in surveillance of patients with hepatocellular carcinoma candidates for liver transplantation.
Article in La Radiologia medica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare the diagnostic performance of three different abbreviated MRI protocols simulated by extraction from a standard liver MRI protocol with hepatobiliary-specific contrast agent obtained for hepatocellular carcinoma (HCC) surveillance in patients candidates for liver transplantation.
methodsWe conducted a retrospective study on cirrhotic patient population, undergoing MRI surveillance for HCC. All patients were candidates to liver transplantation with a total of 105/195 patients previously treated with liver-directed therapy. From the complete liver MRI with hepatobiliary-specific contrast agent (cMRI), three simulated abbreviated MRI protocols were extracted: dynamic contrast-enhanced abbreviated MRI (Dyn-AMRI); hepatobiliary phase abbreviated MRI (HBP-AMRI) and non-enhanced abbreviated MRI (NE-AMRI). Three abdominal radiologists independently interpreted the simulated protocols.
results195 cirrhotic patients, candidates for liver transplantation, were analyzed. The overall sensitivity, specificity and accuracy of AMRI for HCC detection were 94%, 96% and 94% for Dyn-AMRI, 93%, 94% and 93% for HBP-AMRI, 90%, 90% and 90% for NE-AMRI. The interchangeability analysis revealed no significant difference between HBP-AMRI and cMRI and between cMRI and Dyn-AMRI. Regarding equivalence, agreement and interchangeability analysis, no significant differences were found in detection of HCC in patients previously undergoing liver-directed therapy.
conclusionBoth Dyn-AMRI and HBP-AMRI could be used in surveillance of cirrhotic patients, even after previous liver-direct therapy.
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