Evidence map›Paper›PMID 42440099›Full record

ArticlePediatric radiology2026

Developmental venous anomalies on fetal magnetic resonance imaging: prevalence and reproducible radiological phenotypes.

Stephanie Libzon, Moran Hausman-Kedem, Nira Schneebaum-Sender, Li-Tal Pratt, Zvi Leibovitz, Gustavo Malinger, Karina Krajden Haratz, Shelly I Shiran, Catherine Garel, Liat Ben Sira

Abstract read
In one paragraph

Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Stephanie LibzonPediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky University Medical Center (Ichilov), 6 Weizmann Street, Tel Aviv, 6423906, Israel. steph.libzon@gmail.com.
Moran Hausman-KedemPediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky University Medical Center (Ichilov), 6 Weizmann Street, Tel Aviv, 6423906, Israel.
Nira Schneebaum-SenderPediatric Neurology Institute, Dana-Dwek Children's Hospital, Tel Aviv Sourasky University Medical Center (Ichilov), 6 Weizmann Street, Tel Aviv, 6423906, Israel.
Li-Tal PrattGray Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Zvi LeibovitzObstetrics & Gynecology Ultrasound Unit, Bnai Zion Medical Center, Haifa, Israel.
Gustavo MalingerDivision of Ultrasound in Obstetrics and Gynecology, Lis Maternity and Women's Hospital, Tel Aviv Sourasky University Medical Center (Ichilov), Tel Aviv, Israel.
Karina Krajden HaratzGray Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Shelly I ShiranGray Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel.
Catherine GarelPediatric Radiology, Department of Radiology, Dana-Dwek Children's Hospital, Tel Aviv Sourasky University Medical Center (Ichilov), Tel Aviv, Israel.
Liat Ben SiraGray Faculty of Medical and Health Science, Tel Aviv University, Tel Aviv, Israel. bensiraliat@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDevelopmental venous anomalies are the most common cerebral vascular malformations but remain underrecognized in fetuses. Accurate prenatal identification is important for diagnosis and counseling.

objectiveThis study aimed to describe the prevalence of developmental venous anomalies on fetal MRI and characterize their distinctive MRI patterns. MATERIALS AND

methodsA retrospective study of all fetal MRIs performed between January 2017 and June 2025. Cases with documented or suspected developmental venous anomalies were extracted, including a systematic re-evaluation of studies with susceptibility artifacts, to identify developmental venous anomalies not categorized initially as such. Two independent reviewers assessed the number, location, and drainage pattern (superficial, deep, or mixed) of developmental venous anomalies. Associated abnormalities, including varix thrombosis, parenchymal hemorrhage and volume loss, and vascular malformation, were recorded. Developmental venous anomalies with associated abnormalities or multiple developmental venous anomalies were classified as complicated developmental venous anomalies.

resultsAmong 3,932 fetuses, 18 (0.46%) had developmental venous anomalies (median gestational age 33 weeks (IQR, 32, 33); 13 males). Developmental venous anomalies were frontal in 10 (55.6%), parieto-occipital in 7 (38.9%), and parietal in 1 (5.6%); 14 (77.8%) were right-sided. Deep drainage occurred in 8/18 (44.4%), superficial in 4/18 (22.2%), and mixed in 6/18 (33.3%). Two reproducible MRI patterns were identified: the "fisherman's-rope" sign in superficial frontal developmental venous anomalies, and ventricular-wall T2 hypointensity in developmental venous anomalies with deep drainage. Eight fetuses (44.4%) had a complicated developmental venous anomaly. Multiple developmental venous anomalies (3/18, 16.7%) were associated with varix thrombosis (2/3 vs 0/15, P=0.02).

conclusionFetal developmental venous anomalies demonstrate two reproducible MRI patterns that enable confident diagnosis and help in differentiating from hemorrhage and other vascular malformations.

Indexed as

Cerebral VeinsMagnetic Resonance ImagingPrenatal DiagnosisFemaleHumansMalePhenotypePregnancyPrevalenceReproducibility of ResultsRetrospective StudiesDevelopmental venous anomaliesFetalHemorrhageMagnetic resonance imagingPrenatal diagnosisVascular malformation

Identifiers

PMID42440099
PMCPMC13407610

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