Evidence map›Paper›PMID 42440033›Full record

ArticleClinical journal of gastroenterology2026

A young pregnant woman with oesophageal cancer who responded to carboplatin plus nab-paclitaxel therapy.

Yoshinori Kikuchi, Kazuhisa Yamaguchi, Munehiro Wakabayashi, Naobumi Tochigi, Naoyuki Harada, Atsuro Terahara, Takahisa Matsuda

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshinori KikuchiDepartment of Clinical Oncology, Faculty of Medicine, Toho University, 6-11-1 Ota-ku, Tokyo, 143-8541, Japan. y-kikuchi@med.toho-u.ac.jp.ORCID http://orcid.org/0000-0001-6070-6927
Kazuhisa YamaguchiDivision of Gastroenterology and Hepatology, Department of Internal Medicine (Omori), Faculty of Medicine, Toho University, Tokyo, Japan.
Munehiro WakabayashiDivision of Gastroenterology and Hepatology, Department of Internal Medicine (Omori), Faculty of Medicine, Toho University, Tokyo, Japan.
Naobumi TochigiDepartment of Pathology, Faculty of Medicine, Toho University, Tokyo, Japan.
Naoyuki HaradaDepartment of Neurosurgery (Omori), Faculty of Medicine, Toho University, Tokyo, Japan.
Atsuro TeraharaDepartment of Radiology (Omori), Faculty of Medicine, Toho University, Tokyo, Japan.
Takahisa MatsudaDivision of Gastroenterology and Hepatology, Department of Internal Medicine (Omori), Faculty of Medicine, Toho University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case involved a 35-year-old female patient in the fifth month of pregnancy. The patient complained of dysphagia in the early stages of pregnancy and was referred to our hospital after developing dyspnea. An MRI revealed an 8 cm tumor in the anterior mediastinum compressing the airway. The fetus was delivered via emergency cesarean section, and a cervical lymph node biopsy confirmed squamous cell carcinoma. The tumor was diagnosed as an anterior mediastinal tumor of unknown primary origin, and treatment with nanoparticle albumin-bound paclitaxel (nab-PTX) plus Carboplatin (CBDCA) resulted in significant tumor shrinkage. Following shrinkage, the tumor was ultimately diagnosed as esophageal cancer. Subsequently, recurrence in the esophagus and brain metastasis were detected. Still, after undergoing radiation therapy, surgical treatment, and chemotherapy, no recurrence was observed for more than one year after the final treatment. The results of this study demonstrate that the combination therapy of nab-PTX plus CBDCA is highly effective not only for lung squamous cell carcinoma but also for esophageal squamous cell carcinoma.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCarcinoma, Squamous CellEsophageal NeoplasmsPregnancy Complications, NeoplasticAdultAlbuminsBrain NeoplasmsCarboplatinFemaleHumansPaclitaxelPregnancy130-nm albumin-bound paclitaxelAlbuminsCarboplatinPaclitaxelChemotherapyEsophageal cancernab-PTXRadiation

Identifiers

PMID42440033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.