Evidence map›Paper›PMID 42439927›Full record

ArticleSurgery today2026

Tracheostomy after living donor liver transplantation: the incidence, risk factors, and prognostic significance.

Kantoku Nagakawa, Yuta Kawaguchi, Akihiko Soyama, Hajime Matsushima, Yerko Blanco Fernandez, Ayaka Kinosihita, Kazushige Migita, Takashi Hamada, Tomohiko Adachi, Susumu Eguchi

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Article in Surgery today, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Kantoku NagakawaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Yuta KawaguchiDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Akihiko SoyamaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan. soyama@tokushima-u.ac.jp.ORCID http://orcid.org/0000-0003-2932-4300
Hajime MatsushimaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Yerko Blanco FernandezDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Ayaka KinosihitaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Kazushige MigitaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Takashi HamadaDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Tomohiko AdachiDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.
Susumu EguchiDepartment of Surgery, Division of Digestive Surgery and Transplantology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1, Sakamoto, Nagasaki, 852-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTracheostomy after living donor liver transplantation (LDLT) often indicates a complicated postoperative course. However, data on its incidence, risk factors, and outcomes are limited. This study aimed to identify the predictors and prognostic factors related to postoperative tracheostomy and in-hospital mortality.

methodsWe retrospectively reviewed the records of 228 adult LDLT recipients between 2008 and 2023. Patients were divided into tracheostomy (T, n = 33) and non-tracheostomy (NT, n = 195) groups. The clinical characteristics, perioperative factors, and postoperative complications were compared. Risk factors for tracheostomy and prognostic factors for in-hospital mortality were evaluated using univariate and multivariate logistic regression analyses.

resultsTracheostomy was performed in 33 patients (14.5%). Postoperative pneumonia, hepatic artery thrombosis (HAT), and small-for-size syndrome (SFSS) were identified as independent risk factors. In-hospital mortality was higher in the T group than in the NT group (45.5% vs. 8.2%, p < 0.01). A multivariate analysis revealed that total bilirubin on postoperative day 7 and tracheostomy timing were independent prognostic factors, with hyperbilirubinemia and delayed tracheostomy associated with increased mortality.

conclusionPatients who required tracheostomy after LDLT had poorer survival rates. Early stabilization of graft function and optimized systemic management that enable earlier tracheostomy when required may be important.

Indexed as

Hepatic artery thrombosisLiving donor liver transplantRespiratory failureSmall for size syndromeTracheostomy

Identifiers

PMID42439927

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