ArticleInquiry : a journal of medical care organization, provision and financing
Symptom Severity and Quality of Life Impact in Hyperemesis Gravidarum and Nausea of Pregnancy: Evidence From a Large Cross-Sectional Study.
Article in Inquiry : a journal of medical care organization, provision and financing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
IntroductionThis study aimed to evaluate the severity of symptoms and their impact on quality of life among women experiencing hyperemesis gravidarum (HG) and nausea and vomiting of pregnancy (NVP).MethodsA cross-sectional study was conducted in hospitals and primary healthcare centers. Data were collected using validated questionnaires that contained the Windsor 2021 criteria for HG diagnosis, PUQE-24 for symptom severity, and NVPQoL for health-related QoL.ResultsAmong 380 participants, 167 (43.9%) met the Windsor 2021 criteria for HG. The mean PUQE-24 score was 5.4 ± 2.5, with 112 (29.4%) reporting moderate to severe symptoms. A prior history of HG was strongly associated with current HG diagnosis (OR = 3.47, 95% CI: 1.55-7.80, p = 0.003) and increased PUQE scores by 1.58 points (p < 0.001). PUQE score itself was a significant associated factor, with each one-point increase linked to a 30% higher likelihood of HG diagnosis (OR = 1.30, 95% CI: 1.15-1.48, p < 0.001). Gestational age was inversely related to severity (B = -0.06 per week, SE = 0.01, p < 0.001). Unhealthy or special diets were associated with higher PUQE scores (B = 0.67, SE = 0.30, p = 0.024). Each unit increase in PUQE score was linked to a 6.18-point rise in NVPQoL scores (p < 0.001). A current HG diagnosis was also significantly associated with poorer QoL, contributing to a 17.79-point increase in NVPQoL scores (p < 0.001).ConclusionsThis study provides the first comprehensive application of validated diagnostic and severity tools for NVP and HG in Palestine, highlighting global risk factors such as prior history of HG and gestational age, as well as region-specific determinants including dietary patterns and limited access to evidence-based pharmacological treatments. Findings are informative for clinicians, policymakers, and researchers, underscoring the need for context-sensitive guidelines and inclusive maternal health strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.