Evidence map›Paper›PMID 42439694›Full record

ArticleCells2026

STEAP4-Mediated ROS-TERT-TP53 Signaling Promotes Granulosa Cell Dysfunction in Experimental Models of Polycystic Ovary Syndrome.

Xinxin Quan, Xue Xue, Huilan Ma, Lei Yang, Chen Chen, Yu Liu, Kejie Yao, Hui Yang, Rongxiang Wang, Liya Shi and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinxin QuanDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Xue XueDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Huilan MaDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Lei YangDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Chen ChenDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Yu LiuDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Kejie YaoDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Hui YangDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Rongxiang WangDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Liya ShiDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Lun SuoDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
Qiuju ChenDepartment of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.ORCID 0000-0001-7635-4401
Lihua SunDepartment of Cardiovascular Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.

Funding

National Natural Science Foundation of China 82271663National Natural Science Foundation of China 82301961the National Key Research & Development Program of China 2024YFA1108100
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Granulosa CellsMembrane ProteinsOxidoreductasesPolycystic Ovary SyndromeReactive Oxygen SpeciesTumor Suppressor Protein p53AnimalsApoptosisCell LineCell ProliferationDehydroepiandrosteroneDisease Models, AnimalFemaleHumansMiceMice, Inbred C57BLDehydroepiandrosteroneMembrane ProteinsOxidoreductasesReactive Oxygen SpeciesSTEAP4 protein, humanTumor Suppressor Protein p53oxidative stressP53 pathwayPCOSSTEAP4TERT

Identifiers

PMID42439694
PMCPMC13359901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.