Evidence map›Paper›PMID 42439693›Full record

ArticleCells2026

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Julian Bauer, Sofia Mnuskina, Anette Wirth-Hücking, Michael Haug, Dominik Schneidereit, Stefanie Nübler, Lucas Kreiß Roohian, Sebastian Schürmann, Nicola Cacciani, Lars Larsson and 1 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julian BauerInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Sofia MnuskinaInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Anette Wirth-HückingInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0001-5866-5492
Michael HaugInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0001-5968-2593
Dominik SchneidereitInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Stefanie NüblerInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Lucas Kreiß RoohianInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0002-7749-0015
Sebastian SchürmannInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.
Nicola CaccianiDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden.
Lars LarssonDepartment of Clinical Sciences, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden.
Oliver FriedrichInstitute of Medical Biotechnology, Department of Chemical and Biological Engineering, Friedrich-Alexander University Erlangen-Nürnberg, Paul-Gordan-Str. 3, 91052 Erlangen, Germany.ORCID 0000-0003-2238-2049

Funding

Federal Ministry of Research, Technology and Space 03DPS1190AGerman Research Foundation 326998133
6 · The paper itself

Abstract

Critical illness myopathy (CIM) is linked to mechanical ventilation and complete mechanical muscle silencing in intensive care unit (ICU) patients. Limb muscles show atrophy and declined specific single fibre force through altered protein turnover and diminished myosin-to-actin ratios. A rat ICU model reproducing preferential myosin loss and specific force decline in limb muscle was used to assess myofibrillar remodelling. After 5 or 10 days of ICU intervention, single

Indexed as

Critical IllnessGlucocorticoidsMolecular ChaperonesMuscle Fibers, SkeletalAnimalsMaleMuscle, SkeletalMyofibrilsOximesPiperidinesPrednisoloneRatsBGP 15GlucocorticoidsMolecular ChaperonesOximesPiperidinesPrednisolone3D cytoarchitectureBGP-15critical illness myopathyedl musclequantitative morphometryremodellingSecond Harmonic Generationsoleus muscle

Identifiers

PMID42439693
PMCPMC13360227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.