In one paragraphArticle in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Baffour Kyei SarpongDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0009-0005-6726-3125 Niklas RilkeDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0000-0002-0283-5832 Lea JoswigDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0009-0005-5642-267X Finn SpechtDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0009-0003-6847-5889 Mona Shaygan TabarDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0009-0000-5105-295X Alina BluschBrain Disease Biomarker Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, Medical Faculty, Lund University, 223 62 Lund, Sweden.
Anna MeichsnerDepartment of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany.ORCID 0009-0005-1229-5808 Pia RenkDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
Xiomara PedreiturriaDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0000-0002-3024-3826 Thomas GrüterDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0000-0001-8927-9818 Rafael KlimasDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0000-0001-5989-2195 Konstanze F WinklhoferDepartment of Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany.
Ralf GoldDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
Melissa SgodzaiDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.
Kalliopi PitarokoiliDepartment of Neurology, St. Josef-Hospital, Ruhr University Bochum, Gudrunstr. 56, 44791 Bochum, Germany.ORCID 0000-0002-2483-4929 Funding
Deutsche Forschungsgemeinschaft 401510699Deutsche Forschungsgemeinschaft 492434978Deutsche Forschungsgemeinschaft EXC 2033 - 390677874
6 · The paper itselfAbstract
Neurodegeneration and oxidative stress are central drivers of immune-mediated neuropathies. Capsaicin, the active ingredient in chili pepper and a direct agonist of the transient receptor potential vanilloid (TRPV1) channel, is used clinically to treat neuropathic pain. We previously demonstrated immunomodulatory and antioxidative effects of capsaicin in experimental autoimmune neuritis in vivo and Schwann cells (SC) in vitro. However, the molecular mechanisms underlying the maintenance of axonal integrity in dorsal root ganglion (DRG) and SC homeostasis remain unclear. In this study, we described the effects of capsaicin on DRG and SC in vitro under both naïve and S-Nitroso-N-acetyl-DL-penicillamine (SNAP)-induced oxidative stress conditions. Capsaicin induced an upregulation of the antioxidative cascade involving
Indexed as
CapsaicinGanglia, SpinalOxidative StressRegenerationSchwann CellsTRPV Cation ChannelsAnimalsAntioxidantsMitochondriaNF-E2-Related Factor 2RatsAntioxidantsCapsaicinNF-E2-Related Factor 2TRPV Cation Channelscapsaicinchronic inflammatory demyelinating polyneuropathydorsal root gangliaoxidative stressregenerationSchwann cells
Identifiers
PMID42439619
PMCPMC13360480
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