Evidence map›Paper›PMID 42439566›Full record

ArticlemBio2026

Feedback GABA signaling suppresses white spot syndrome virus infection via mTORC1-mediated autophagy inhibition in shrimp.

Jie Gao, Ye-Jia Song, Xin-Shuang Zhang, Dong-Dong Han, Dongwei Kang, Yingjie Li, Xian-Wei Wang

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie GaoSchool of Life Sciences, Shandong University, Qingdao, China.ORCID 0009-0009-3587-5740
Ye-Jia SongSchool of Life Sciences, Shandong University, Qingdao, China.
Xin-Shuang ZhangSchool of Life Sciences, Shandong University, Qingdao, China.
Dong-Dong HanSchool of Life Sciences, Shandong University, Qingdao, China.
Dongwei KangDepartment of Medicinal Chemistry, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0001-9232-953X
Yingjie LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID 0009-0000-4437-6630
Xian-Wei WangSchool of Life Sciences, Shandong University, Qingdao, China.ORCID 0000-0002-6811-1482

Funding

National Natural Science Foundation of China 32303041National Natural Science Foundation of China 32525058National Natural Science Foundation of China 32573550Natural Science Foundation of Shandong Province ZR2024JQ038
6 · The paper itself

Abstract

Gamma-aminobutyric acid (GABA) is a neurotransmitter whose role in virus-host interactions remains poorly defined. Here, we show that GABA restricts white spot syndrome virus (WSSV) infection by suppressing virus-induced autophagy in kuruma shrimp

Indexed as

Autophagygamma-Aminobutyric AcidMechanistic Target of Rapamycin Complex 1PenaeidaeSignal TransductionWhite spot syndrome virus 1AnimalsCalciumHost-Pathogen InteractionsReceptors, GABA-ACalciumgamma-Aminobutyric AcidMechanistic Target of Rapamycin Complex 1Receptors, GABA-Aautophagygamma-aminobutyric acidshrimpwhite spot syndrome virus

Identifiers

PMID42439566
PMCPMC13463846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.