ArticleOpen respiratory archives
Radical Endobronchial Brachytherapy: A Therapeutic Alternative in Selected Cases.
Article in Open respiratory archives. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
5 authors.
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Abstract
A 75-year-old male, former smoker (50 pack-years), with a history of squamous cell lung carcinoma treated with right lower lobectomy 20 years earlier, presented with progressive dyspnea at rest (mMRC IV) and hypoxemic respiratory failure. Chest computed tomography revealed a 14 mm nodular lesion in the left main bronchus. Bronchoscopy showed a lesion at the carina between the left upper and lower lobes, causing near-complete obstruction. Biopsy and partial endoscopic resection were performed, but follow-up demonstrated slight progression. Histopathology confirmed squamous cell carcinoma. Due to prior lobectomy, surgery was ruled out, and radical high-dose-rate endobronchial brachytherapy with Iridium-192 (30 Gy in six weekly fractions) was administered. Complete endobronchial resolution was achieved and maintained at six months. Endobronchial brachytherapy is a well-tolerated technique that delivers high radiation doses with minimal damage to surrounding tissue and may represent a radical therapeutic option in selected patients with localized endobronchial tumors not eligible for surgery or external radiotherapy.
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