ArticleClinical ophthalmology (Auckland, N.Z.)2026
Comparative Analysis of Corneal Endothelial Cell Loss After Phacoemulsification in Microcornea versus Normal-Sized Corneas.
Article in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Phacoemulsification is inevitably accompanied by loss of corneal endothelial cells, and microcornea eyes with crowded anterior segments may be more susceptible to this damage. Purpose: This study aimed to compare endothelial cell loss (ECL) after cataract phacoemulsification surgery between eyes with microcornea and those with normal-sized corneas. Methods: This retrospective study included 50 eyes from 50 patients with microcornea and 120 eyes from 120 patients with normal-sized corneas who underwent phacoemulsification. Demographic data and biometric parameters were evaluated preoperatively. Postoperative corneal endothelial cell parameters were measured 3 months after surgery. Results: Compared with the normal controls, the microcornea group had a shallower anterior chamber, thicker lens and shorter white-to-white distance (WTW) (P < 0.01). Additionally, at 3 months postoperatively, the microcornea group had significantly greater ECL (662.20 ± 496.79 cells/mm Conclusion: Compared with normal-sized corneas, microcorneas were more prone to endothelial cell loss after phacoemulsification. WTW was a significant risk factor for postoperative ECL. Preoperative measurement of WTW may serve as a useful risk stratification tool to identify patients who may require additional endothelial protective measures during cataract surgery.
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