ArticleKidney international reports2026
PREDICT Tool for Pregnancy-Associated CKD Progression.
Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
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Abstract
Introduction: Prepregnancy counselling is recommended for women with chronic kidney disease (CKD) to discuss potential adverse outcomes; however, no tools exist to estimate individual risk. We aimed to develop and externally validate 2 prediction models for outcomes prioritized by people with CKD and health care professionals: The primary outcome was the probability of ≥25% reduction in estimated glomerular filtration rate (eGFR) or kidney replacement therapy (KRT) within 12 months postpartum. The secondary outcome was the probability of small-for-gestational-age (SGA) (< 3rd percentile) infant and/or preterm delivery (< 34 weeks). Methods: The development cohort used linked data from the National Registry of Rare Kidney Disease (RaDar), UK Renal Registry (UKRR) and NHS Hospital Episode Statistics (HES). Individuals with eGFR < 90 ml/min per 1.73 m Results: The development cohort included 746 women (median prepregnancy eGFR: 58 ml/min per 1.73 m Conclusion: We developed high performing models for individuals with CKD to predict coselected adverse kidney and neonatal outcomes from contemporaneous cohorts. Individualized pregnancy risk assessment tools could support future parents and health care professionals to make informed choices.
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