ArticleCureus2026
Benchmark Comparison of Bone Marrow Aspiration Systems: Increased Progenitor Cell Concentrations Achieved Without Centrifugation Using a Novel Filtration Design With High Surface Area.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background Bone marrow aspirate (BMA) is widely used in orthopedic and regenerative procedures due to its content of mesenchymal stromal cells (MSCs), hematopoietic progenitors, and supportive cellular elements that contribute to bone healing and tissue repair. Conventional bone marrow aspiration techniques are limited by progressive hemodilution, in which peripheral blood increasingly contaminates the aspirate as volume is drawn from a fixed location. This process both reduces MSC and progenitor concentrations and increases variability in aspirate samples. Objectives The purpose of this study was to characterize the cell yield of a novel bone marrow aspiration system (B-MAN™ Bone Marrow Aspiration System, SurGenTec, Boca Raton, FL) under standardized testing conditions. These results were compared with published benchmark data from a study that analyzed centrifuge-processed bone marrow concentrate (BMAC) systems and a no-spin aspiration device analyzed in the same reference laboratory used in this study. Methods A retrospective analysis was performed on bone marrow aspirate obtained from the anterior iliac crest of five adult male subjects (age range 18-44) using the B-MAN™ system during elective orthopedic procedures. Procedures included anterior cruciate ligament reconstruction, hip labral repair, anterior cruciate ligament
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