ArticleNanoscale advances2026
Monodisperse PEG engineering for quantifiable surface conjugation on PLGA nanoparticles.
Article in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Surface PEGylation is a well-established strategy to enhance the stability, functionality, and bioavailability of nanoparticles (NPs) in biomedical applications. However, the widespread use of polydisperse PEG derivatives limits the ability to precisely quantify surface PEGylation efficiency (mol%) and evaluate its effect on NP properties. In this study, we present a systematic approach to engineer PLGA NPs using structurally defined monodisperse PEG-diamine derivatives of varying chain lengths (PEG6, PEG26, PEG45), synthesized and purified by chromatographic methods and covalently attached
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