Evidence map›Paper›PMID 42438446›Full record

ArticleJournal of microbiology and biotechnology2026

A Diastereomeric Hydroxycurvularin Mixture Inhibits Melanogenesis and Inflammation

Ja-Hun Seo, Hyun-Su Koo, Van-Hieu Mai, Su-Bin Kim, Gi-Hyeon Seong, Thuong T T Nguyen, Jeong-Eun Seon, Ha-Rim Choi, Hyang Burm Lee, Won-Keun Oh and 1 more

Abstract read
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In one paragraph

Article in Journal of microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ja-Hun SeoSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.
Hyun-Su KooSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.
Van-Hieu MaiResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Su-Bin KimSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.
Gi-Hyeon SeongResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Thuong T T NguyenDepartment of Agricultural Biological Chemistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Jeong-Eun SeonSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.
Ha-Rim ChoiDepartment of Nursing, Nambu University, Gwangju 62271, Republic of Korea.
Hyang Burm LeeDepartment of Agricultural Biological Chemistry, Chonnam National University, Gwangju 61186, Republic of Korea.
Won-Keun OhResearch Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Hyung-Sik KangSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal metabolites serve as a prolific source of structurally diverse bioactive compounds with significant potential for skin health and pigmentation regulation. In this study, two diastereomers of 11-hydroxycurvularin (compounds 1 and 2) and curvularin (compound 3) were isolated from

Indexed as

CytokinesInflammationMelanogenesisMonophenol MonooxygenaseAnimalsAnti-Inflammatory AgentsAscomycotaInterleukin-1betaMacrophagesMelaninsMelanoma, ExperimentalMiceRAW 264.7 CellsReactive Oxygen SpeciesAnti-Inflammatory AgentsCytokinesInterleukin-1betaMelaninsMonophenol MonooxygenaseReactive Oxygen SpeciesCurvularia intermediaDermatological potentialFungal polyketidesHydroxycurvularinMelanogenesisPigmentation regulation

Identifiers

PMID42438446
PMCPMC13372789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.