Evidence map›Paper›PMID 42438103›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2026

Standardised Pfannenstiel versus supraumbilical muscle-sparing transverse extraction sites in colon cancer surgery: An IDEAL stage 4 report.

Maja Christine Rasmussen, Niklas Nygaard Baastrup, Anna Sofie Friis Olsen, Anders Kierkegaard Gundestrup, Charlotte Tiffanie Bendtz Kanstrup, Jakob Kleif, Claus Anders Bertelsen

Abstract readComparative Study
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maja Christine RasmussenDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0009-0008-9816-3778
Niklas Nygaard BaastrupDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0002-4399-8013
Anna Sofie Friis OlsenDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0003-1121-8489
Anders Kierkegaard GundestrupDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0001-5767-0089
Charlotte Tiffanie Bendtz KanstrupDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0001-8455-3654
Jakob KleifDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0002-9330-0410
Claus Anders BertelsenDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hillerød, Denmark.ORCID 0000-0001-6337-8447

Funding

Helen Rudes FondInger & Hakon Fabricius FondOlga Bryde Nielsen Fond
6 · The paper itself

Abstract

aimTo compare long-term incisional hernia (IH) risk between Pfannenstiel and supraumbilical muscle-sparing transverse extraction sites following minimally invasive colon cancer surgery with standardised fascial closure. Reported according to the IDEAL framework (Stage 4).

methodThis single-centre study included patients (Stages I-III colon adenocarcinoma, 2014-2017) undergoing laparoscopic resection via Pfannenstiel or supraumbilical incisions. Fascial closure used continuous slowly absorbable poly-4-hydroxybutyrate sutures (ratio ≥ 4:1). The primary endpoint was CT-verified IH at the extraction site at 5 years. Inverse Probability of Treatment Weighting (IPTW) adjusted for baseline covariates.

resultsThe final cohort comprised 245 patients (Pfannenstiel, n = 141; supraumbilical, n = 104). The median follow-up was 5.3 and 5.6 years, respectively. In the unadjusted analysis, the 5-year IH risk was 15.4% (95% CI: 9.5-21.3) for Pfannenstiel and 18.8% (95% CI: 11.2-26.4) for supraumbilical incisions (p = 0.49). Following IPTW adjustment, the estimated risks were 14.6% (95% CI: 8.9-20.3) and 13.6% (95% CI: 7.7-19.4), respectively (adjusted risk difference - 1.0%; 95% CI: -9.2-7.2, p = 0.81). Only two (0.8%) of the 245 patients underwent surgical hernia repair.

conclusionThe IH risk seems not associated with the extractions site incision, Pfannenstiel and supraumbilical muscle-sparing transverse extraction sites, when standardised closure techniques are applied. These findings challenge the assumption that Pfannenstiel sites are inherently superior for hernia prevention. The choice of extraction site based on anastomosis technique may not be justified; instead, it should be guided by oncological requirements and procedural ergonomics rather than perceived differences in hernia risk.

trial registrationDanish Patient Safety Authority (#31-1522-51).

Indexed as

AdenocarcinomaColectomyColonic NeoplasmsIncisional HerniaLaparoscopyOrgan Sparing TreatmentsAgedFemaleHumansMaleMiddle AgedUmbilicuscolon cancer resectioncomputed tomographyincisional herniaminimally invasive surgeryPfannenstieltransverse muscle‐sparing

Identifiers

PMID42438103
PMCPMC13358024

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.