ArticleMacromolecular rapid communications2026
Photocontrolled Drug Release From Donor-Acceptor Stenhouse Adduct Amphiphile Doped Laden Polymeric Hydrogel.
Article in Macromolecular rapid communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Photocontrolled Drug Release From Donor-Acceptor Stenhouse Adduct Amphiphile Doped Laden Polymeric Hydrogel.Macromolecular rapid communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
In chemotherapy, drug dosage should be carefully planned with precise pharmacokinetics. Compared to direct, soluble drug administration, a stimuli-responsive drug delivery material system provided an on-demand medication with minimum adverse effects. Among many stimuli, the use of external red light enables manual remote functionality compared to physiological stimuli such as pH. Herein, a 650 nm red-light-responsive, metal-free hydrogel scaffold for stimuli-responsive drug delivery is reported. The hydrogel network is built by poly(ethylene) glycol thiol and poly(ethylene) glycol acrylate via Michael addition. Donor-acceptor Stenhouse adduct amphiphile (DA), which acts as the moderator of hydrophobic drug doxorubicin, is encapsulated in a polyethylene glycol network to create a drug-loaded hydrogel scaffold. The preparation of DA is purely aqueous and shows a broad absorbance band over 430-800 nm, which enables potential operation in deep tissue. During the drug release experiments, the presence of amphiphile greatly slows the drug release rate in vitro. By using 650 nm laser irradiation, the drug release from amphiphile-encapsulated hydrogel can be triggered after the passive diffusion period. The proposed hydrogel serves as an example of the combination of a photo-switch conjugated amphiphile and a conventional, commercially available polymer hydrogel network, which could serve as a potential smart material for drug delivery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.