Evidence map›Paper›PMID 42437967›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Social network characteristics and cognitive function, decline, and mortality: A joint modeling approach.

Ruijia Chen, Alexander Ivan B Posis, Anna M Pederson, Jingxuan Wang, Andrew K Hirst, L Paloma Rojas-Saunero, Ye Ji Kim, Sebastien Haneuse, Rachel Peterson, Dan Mungas and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ruijia ChenDepartment of Community Health Sciences, UCLA Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California, USA.
Alexander Ivan B PosisDepartment of Public Health Sciences, University of California, Davis, Sacramento, California, USA.
Anna M PedersonDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Jingxuan WangDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Andrew K HirstDivision of Research, Kaiser Permanente Northern California, Pleasanton, California, USA.
L Paloma Rojas-SauneroDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California, USA.
Ye Ji KimDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Sebastien HaneuseDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Rachel PetersonSchool of Public and Community Health Sciences, University of Montana, Missoula, Montana, USA.
Dan MungasAlzheimer's Disease Research Center, University of California, Davis, Sacramento, California, USA.
Jacqueline M TorresDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA.
Elizabeth Rose MayedaDepartment of Epidemiology, UCLA Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California, USA.
Paola GilsanzDivision of Research, Kaiser Permanente Northern California, Pleasanton, California, USA.
Rachel A WhitmerDepartment of Public Health Sciences, University of California, Davis, Sacramento, California, USA.
Maria M CorradaSchool of Medicine, University of California, Irvine, Irvine, California, USA.
M Maria GlymourDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.

Funding

Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-OldR01AG056519 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Maria Corrada, Paola Gilsanz · 2022 to 2026
$25.8M
Project 4: Social isolation as a driver of AD/ADRD incidence and disparitiesP01AG082653 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Jacqueline Marie Torres · 2024 to 2026
$23.6M
Lifecourse Stressors and Social Disparities in Cognitive Aging: The Roles of Social Networks and Sleep DisturbanceK00AG068431 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHEN, RUIJIA · 2021 to 2024
$330k
Bridging Social Epidemiology and Policy for ADRD Prevention: Effects of Poverty Alleviation Policies on Alzheimer's Disease and Related Dementias Risk and DisparitiesK99AG088369 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Ruijia Chen · 2025 to 2026
$264k
The Impact of SARS-CoV-2 Infection and Vaccination on the Risk of Alzheimer’s Disease and Related DementiasK00AG083306 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Jingxuan Wang · 2025 to 2026
$174k
Occupational Determinants of Cognitive and Brain Health Among Middle-Aged and Older Latinos in the U.S.K99AG093067 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Liliana Paloma Rojas Saunero · 2026 to 2026
$124k
Alzheimer's Association AARFD-24-1308786NIA NIH HHS K00 AG068431NIA NIH HHS K00AG068431NIA NIH HHS K00 AG083306NIA NIH HHS K00AG083306NIA NIH HHS K99 AG088369NIA NIH HHS K99AG088369NIA NIH HHS K99 AG093067NIA NIH HHS K99AG093067NIA NIH HHS P01 AG082653NIA NIH HHS P01AG082653NIA NIH HHS R01 AG056519NIA NIH HHS R01AG056519
6 · The paper itself

Abstract

introductionMaintaining social relationships is challenging in advanced old age due to frequent changes in social networks. Little is known about whether social networks are associated with cognitive function, decline, and mortality in this population, or whether these associations differed by sex/gender.

methodsParticipants aged ≥90 years (n = 677; mean age = 92.9, SD = 2.2) from the multi-ethnic LifeAfter90 Study completed cognitive testing every 6 months (2019-2022). Joint models examined associations of social networks with cognitive decline and mortality, overall, and by sex/gender.

resultsOver 1.63 years of follow-up, 163 (24%) participants died. Baseline structural and functional social network characteristics were associated with higher executive function and verbal episodic memory, with consistent findings across sex/gender. Social networks did not predict cognitive decline or mortality. DISCUSSION: Among adults aged 90+, social networks were linked to better cognitive function but not to short-term cognitive decline or mortality.

Indexed as

CognitionCognitive DysfunctionMortalitySocial NetworkingAged, 80 and overExecutive FunctionFemaleHumansMaleNeuropsychological TestsSocial Support90+cognitive declinecognitive functionmortalitysocial network

Identifiers

PMID42437967
PMCPMC13357703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.