Evidence map›Paper›PMID 42437698›Full record

ArticleBMJ quality & safety2026

When emergency physicians meet patients displaying irritable behaviours: a randomised vignette-based experiment investigating physicians' emotions and clinical reasoning.

Linda M Isbell, Nathan R Huff, Guanyu Liu, Howard Bessen, Vincent Kan, Isabella Levesque, Matthew Bird, Peter Smulowitz

Abstract read
In one paragraph

Article in BMJ quality & safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linda M IsbellPsychological and Brain Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA lisbell@umass.edu.ORCID http://orcid.org/0000-0003-3467-3548
Nathan R HuffPsychological and Brain Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA.ORCID http://orcid.org/0000-0002-5844-9527
Guanyu LiuPsychological and Brain Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA.
Howard BessenEmergency Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
Vincent KanEmergency Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.ORCID http://orcid.org/0000-0003-2891-5686
Isabella LevesquePsychological and Brain Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA.ORCID http://orcid.org/0009-0009-2497-8189
Matthew BirdPsychological and Brain Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA.
Peter SmulowitzEmergency Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.ORCID http://orcid.org/0000-0002-4155-6844

Funding

AHRQ HHS R01 HS025752
6 · The paper itself

Abstract

backgroundClinical encounters with patients who display challenging behaviours (eg, rude, demanding) are increasingly common in emergency departments and can heighten negative emotions, compromise healthcare quality and impact physician well-being. This study investigated the influence of patients' irritable behaviours on physicians' emotions, clinical assessments, decisions and behaviours, and the extent to which physicians' predispositions to experience anxiety and concern about bad clinical outcomes (ie, stress from uncertainty) may magnify these effects. We also explored whether these effects differed if patients had a stigmatised condition (mental illness history).

methodsExperienced emergency physicians (n=134) completed a randomised vignette-based experiment between June and August 2022. Physicians assessed four patients in computer-simulated, interactive clinical encounters in which patient behaviour (irritable vs calm) and mental illness history (present vs absent) were varied within subjects. Physicians viewed each patient's health record, a video-recorded encounter and physical exam results, and provided patient assessments, clinical decisions, ordered tests and reported a diagnosis. Physicians also reported their emotional reactions to each patient and completed the Stress from Uncertainty Scale (SUS) after assessing all patients. We adhered to the Guideline for Reporting Vignette Experiments.

resultsPhysicians reported greater anger, anxiety and fatigue and less empathy, happiness and engagement during encounters with patients displaying irritable (vs calm) behaviours (all ps<0.001) and evaluated those with irritable behaviours as poorer historians, more likely to be exaggerating pain, less cooperative, engaged, likeable, likely to adhere to treatment and likely to return to work (all ps<0.001). Interactions revealed that SUS amplified the impact of patients' irritable behaviours with high SUS associated with greater physician anger, anxiety and fatigue (all ps≤0.04) and with physicians evaluating these patients as poorer historians, less likely to adhere to treatment and less likeable (all ps≤0.03). Effects were similar regardless of patient mental illness history (all ps>0.60). No effects emerged for clinical decisions, behaviour or diagnosis.

conclusionAlthough patients' irritable behaviours adversely influenced physicians' emotions, engagement and patient assessments, they did not affect the quality of care provided (ie, clinical decisions, behaviour, diagnostic accuracy). Despite this, our findings have important implications. Physicians' reactions to patients displaying irritable behaviours may reduce the quality of physician-patient relationships (eg, reduce trust, effective communication) and contribute to physician burnout-both of which can compromise patient care. Additional research is needed to investigate the multiple ways in which emotional factors can impact patient care quality and safety.

Indexed as

AttitudesCognitive biasesDecision makingEmergency departmentPatient Safety

Identifiers

PMID42437698
PMCPMC13536421

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.