Evidence map›Paper›PMID 42437510›Full record

ReviewJournal of surgical oncology2026

Current Evidence for Circulating Tumor DNA in Sarcoma: Challenges and Opportunities for Clinical Application.

Kristin E Goodsell, Jason A Carter, Hannah R Abrams, Harveshp Mogal, Elizabeth T Loggers, Jeremy Sharib

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristin E GoodsellDepartment of Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-5967-7433
Jason A CarterDepartment of Surgery, University of Washington, Seattle, Washington, USA.
Hannah R AbramsDepartment of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0003-1044-7757
Harveshp MogalDepartment of Surgery, University of Washington, Seattle, Washington, USA.
Elizabeth T LoggersDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Jeremy SharibDepartment of Surgery, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-1047-9823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcomas represent a diverse group of mesenchymal tumors with high rates of recurrence after resection. While recent technical advances have enabled the detection of rare circulating tumor DNA (ctDNA) in other malignancies, the complexity and heterogeneity of sarcoma genomics have historically limited ctDNA in these cancers. This narrative review highlights the rapidly evolving evidence supporting potential clinical applications of ctDNA in common sarcoma subtypes including gastrointestinal stromal tumor, leiomyosarcoma, rhabdomyosarcoma, osteosarcoma, and Ewing sarcoma.

Indexed as

Biomarkers, TumorCirculating Tumor DNASarcomaGastrointestinal Stromal TumorsHumansLeiomyosarcomaBiomarkers, TumorCirculating Tumor DNActDNAgastrointestinal stromal tumorsleiomyosarcomaliquid biopsySarcoma

Identifiers

PMID42437510
PMCPMC13575607

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.