Evidence map›Paper›PMID 42437425›Full record

ArticleHuman cell2026

Daucosterol linoleate from sweet potato inhibits breast cancer metastasis via SCD1 downregulation and suppression of epithelial-mesenchymal transition.

Xintong He, Juan Li, Jun Lu, Zhaomin Chen, Ya Wang, Kehui He, Xuegang Li, Hang Ma, Xiaoli Ye

Abstract read
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In one paragraph

Article in Human cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xintong He *School of Life Sciences, Southwest University, Chongqing, 400715, China.
Juan Li *Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jun LuSchool of Life Sciences, Southwest University, Chongqing, 400715, China.
Zhaomin ChenSchool of Life Sciences, Southwest University, Chongqing, 400715, China.
Ya WangChongqing Youth Vocational and Technical College, Chongqing, China.
Kehui HeSchool of Life Sciences, Southwest University, Chongqing, 400715, China.
Xuegang LiEngineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China.
Hang MaEngineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. hangma@swu.edu.cn.
Xiaoli YeSchool of Life Sciences, Southwest University, Chongqing, 400715, China. yexiaoli@swu.edu.cn.

Funding

County-University Cooperation Innovation Funds of Southwest University SZ202102Science Foundation of the School of Life Sciences, Southwest University 20212005425201Special Key Project of Technology Innovation and Application Development in Chongqing CSTB2021TIAD-KPX0085Special Key Project of Technology Innovation and Application Development in Chongqing CSTC2021jscx-gksb-N0033
6 · The paper itself

Abstract

Breast cancer remains a significant clinical challenge, with treatment failure and patient mortality primarily attributable to tumor metastasis. Daucosterol linoleate (DL) was previously isolated from sweet potato (Ipomoea batatas). Using HPLC analysis of ten commercial dried sweet potato products from different regions of China, DL was detected in all samples, with concentrations ranging from 1.24 mg to 6.05 mg per 100 g, confirming its widespread presence in commercially processed sweet potato products. Pharmacokinetic analysis showed that DL exhibited a peak plasma concentration (C

Indexed as

Breast NeoplasmsDown-RegulationEpithelial-Mesenchymal TransitionIpomoea batatasNeoplasm MetastasisPhytotherapySitosterolsStearoyl-CoA DesaturaseAnimalsCell MovementCell ProliferationFemaleHumansMDA-MB-231 CellslyonisideSCD protein, humanSitosterolsStearoyl-CoA DesaturaseBreast cancerDaucosterol linoleateMetastasisSCD1Sweet potato

Identifiers

PMID42437425

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.