SynthesisAlimentary pharmacology & therapeutics2026
Meta-Analysis: Crohn's Disease Exclusion Diet for Induction and Maintenance in Crohn's Disease.
Synthesis in Alimentary pharmacology & therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-Analysis: Crohn's Disease Exclusion Diet for Induction and Maintenance in Crohn's Disease.Alimentary pharmacology & therapeutics · 2026Pooled it
- Plant and Animal Protein Sources in Inflammatory Bowel Disease: Current Evidence and Clinical Implications.JGH open : an open access journal of gastroenterology and hepatology · 2026Review
- Factors Affecting the Adherence to Partial Enteral Nutrition Combined with the Crohn's Disease Exclusion Diet in Crohn's Disease Adult Patients.Healthcare (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
backgroundThere is a contemporary interest in dietary therapies for the treatment of inflammatory bowel disease. We performed a systematic review and meta-analysis to analyse the clinical effectiveness of the Crohn's disease exclusion diet (CDED) for Crohn's disease (CD).
methodsWe searched PubMed, Embase, and Scopus on 10th February 2025 to identify relevant studies using the terms 'Inflammatory bowel disease OR Crohn's disease' AND 'Crohn's disease exclusion diet'. We extracted information and estimated pooled rates for clinical response, clinical remission, and maintenance of remission with CDED alone, or with partial enteral nutrition (PEN), or exclusive enteral nutrition (EEN). We calculated the odds ratio for outcomes with CDED as compared to controls. Risk of Bias was estimated using RoB-2.0, ROBINS-I, and Joanna Briggs appraisal tools.
resultsOf the 508 titles, eventually 17 were included, and 16 studies provided quantitative data. The overall pooled rates for induction of clinical remission at 6-8 weeks with CDED-based interventions were 0.69 (95% CI: 0.65-0.74, I
conclusionsCDED-based dietary interventions appear to be efficacious for inducing remission in Crohn's disease. Well-designed randomised trials are required to further validate the use of CDED as a whole food approach in the induction and maintenance of remission in Crohn's Disease.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.