Evidence map›Paper›PMID 42437226›Full record

ArticleCureus2026

Ultrasound-Guided Peripheral Nerve Block as the Sole Anesthetic for Above-Knee Amputation in a Patient With Severe Cardiopulmonary Comorbidities.

Dilan Shah, Nakosi Stewart, Bright Kim, Matthew Yoder, Anna Ng-Pellegrino, Sharvil Sharvil Sheth

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dilan ShahDepartment of Surgery, Medical College of Georgia, Augusta, USA.
Nakosi StewartDepartment of Surgery, St. Luke's University Health Network, Bethlehem, USA.
Bright KimDepartment of Anesthesiology, St. Luke's University Health Network, Bethlehem, USA.
Matthew YoderDepartment of Anesthesiology, St. Luke's University Health Network, Bethlehem, USA.
Anna Ng-PellegrinoDepartment of Anesthesiology and Perioperative Medicine, St. Luke's Hospital, Bethlehem, USA.
Sharvil Sharvil ShethDepartment of Vascular Surgery, St. Luke's University Health Network, Bethlehem, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Above-knee amputation (AKA) carries substantial perioperative risk in patients with advanced cardiopulmonary disease for whom general and neuraxial anesthesia are poorly tolerated. Data supporting peripheral nerve blocks (PNBs) as the primary intraoperative anesthetic remain limited. We present a 79-year-old male with extensive cardiopulmonary and metabolic comorbidities who underwent left AKA for chronic limb-threatening ischemia. Ultrasound-guided sciatic, femoral, obturator, and lateral femoral cutaneous nerve blocks using ropivacaine were performed as the sole anesthetic with intravenous midazolam, achieving complete anesthesia without hemodynamic compromise. The Visual Analog Scale score was 0 postoperatively. The technique was reproduced successfully for contralateral amputation, reinforcing the role of PNBs as a primary anesthetic strategy in high-risk patients.

Indexed as

amputation of kneecardiopulmonary diseaseslimb ischemiaperipheral arterial diseaseperipheral nerve blockregional nerve blockultrasound guided

Identifiers

PMID42437226
PMCPMC13355901

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.