Evidence map›Paper›PMID 42437142›Full record

ArticleRadiology case reports2026

Syphilitic descending aortic aneurysm presenting with characteristic double-ring sign on CT: Radiologic-pathologic correlation.

Tsubasa Sugie, Syohei Miyaguni, Nanae Tsuchiya, Yuma Chinen, Hitoshi Inafuku, Tatsuya Maeda, Kojiro Furukawa, Naoki Wada, Akihiro Nishie

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Tsubasa SugieDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Syohei MiyaguniDepartment of Thoracic and Cardiovascular Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Nanae TsuchiyaDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Yuma ChinenDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Hitoshi InafukuDepartment of Thoracic and Cardiovascular Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Tatsuya MaedaDepartment of Thoracic and Cardiovascular Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Kojiro FurukawaDepartment of Thoracic and Cardiovascular Surgery, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Naoki WadaDepartment of Pathology and Oncology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Akihiro NishieDepartment of Radiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his 50s presented with worsening anterior chest pain. Serologic testing revealed active syphilis infection, and polymerase chain reaction testing was positive for COVID-19. Contrast-enhanced computed tomography demonstrated a descending thoracic aortic aneurysm with circumferential wall thickening and a characteristic double-ring sign suggestive of inflammatory aortitis. After blood pressure control and antibiotic therapy, elective descending aortic replacement was performed. Surgical inspection showed diffuse intimal thickening with a tree-bark appearance. Histopathology demonstrated lymphoplasmacytic infiltration in the media, adventitia, and around the vasa vasorum, consistent with syphilitic aortitis. This case highlights the diagnostic value of CT, particularly the double-ring sign, in identifying syphilitic aortitis and demonstrates a rare presentation of syphilitic aneurysm in the descending thoracic aorta.

Indexed as

Computed tomographyDouble-ring signRadiologic–pathologic correlationSyphilitic aortic aneurysmSyphilitic aortitis

Identifiers

PMID42437142
PMCPMC13355744

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