Evidence map›Paper›PMID 42437082›Full record

ReviewBiochemistry and biophysics reports2026

Non-ionizing radiation and cancer: A review on current evidence, mechanistic insights, and public health implications.

Mridula Agrahari, Shruti Gupta, Gaurav Thakur, Shweta Tanwar, Rohit Gautam, Taruna Arora

Abstract readReview
In one paragraph

Review in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mridula AgrahariDivision of Reproductive, Child Health and Nutrition, Indian Council of Medical Research Headquarters, New Delhi, India.
Shruti GuptaDivision of Reproductive, Child Health and Nutrition, Indian Council of Medical Research Headquarters, New Delhi, India.
Gaurav ThakurDivision of Reproductive, Child Health and Nutrition, Indian Council of Medical Research Headquarters, New Delhi, India.
Shweta TanwarIndian Council of Medical Research Headquarters, New Delhi, India.
Rohit GautamDivision of Reproductive, Child Health and Nutrition, Indian Council of Medical Research Headquarters, New Delhi, India.
Taruna AroraDivision of Reproductive, Child Health and Nutrition, Indian Council of Medical Research Headquarters, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-ionizing radiation (NIR) generated from the high power transmission lines, broadcasting antennas and cellular phones represent one of the widespread environmental exposures which can induce carcinogenic outcome. Although NIR lacks sufficient energy to dislodge the electrons for ionization, an indirect mechanism has been proposed to be involved in adverse outcomes under certain exposure conditions. Consequently, radiofrequency electromagnetic field (RF-EMF) exposure remains a consistent scientific and public health concern regarding its possible role in cancer manifestation. This review aims to analyze the findings of RF-EMF exposure and carcinogenicity by integrating epidemiological studies and experimental findings to demonstrate its potential function in cancer manifestation.The available evidence is not sufficient to conclude that RF-EMF exposure is a direct-acting genotoxic carcinogen or cancer initiator. However, laboratory studies have indicated that long-term exposure to non-thermal RF-EMF can cause oxidative stress, genomic instability, epigenetic alterations, ion transport disruption and dysregulation of cell-signaling pathways. These biological effects may contribute to the promotion and progression stages of carcinogenesis, but are not directly responsible for tumor/cancer initiation. The epidemiological evidence significantly varies between extremely low-frequency magnetic fields (ELF-MF) and radiofrequency electromagnetic fields (RF-EMF). Although ELF-MF exposure has demonstrated a more reliable association with childhood leukemia, the data connecting RF-EMF exposure to cancer is less consistent.Studies with the larger sample size and increased exposure duration are needed to strongly corroborate its involvement in cancer development.

Indexed as

Broadcasting antennasCancerNon-ionizing radiationRadio frequency electromagnetic field

Identifiers

PMID42437082
PMCPMC13355819

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.