Evidence map›Paper›PMID 42436812›Full record

ArticleCase reports in anesthesiology2026

Perioperative Pregabalin for Recurrent Intractable Hiccups: A Case Report and Literature Review.

David Lei, Craig T L Yamaguchi, Alastair E Moody, Jeffrey D Swenson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David LeiWestern University of Health Sciences College of Osteopathic Medicine of the Pacific, Pomona, California, USA.ORCID https://orcid.org/0009-0009-1786-7173
Craig T L YamaguchiDepartment of Anesthesiology and Perioperative Medicine, Oregon Health and Science University, Portland, Oregon, USA, ohsu.edu.ORCID https://orcid.org/0000-0002-2730-6283
Alastair E MoodyDepartment of Anesthesiology, Perioperative, and Pain Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA, utah.edu.ORCID https://orcid.org/0000-0002-5232-7705
Jeffrey D SwensonDepartment of Anesthesiology, Perioperative, and Pain Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA, utah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Involuntary diaphragmatic spasms, "hiccups," commonly resolve spontaneously over a few minutes but can occasionally persist, presenting a challenging perioperative problem. Pregabalin is a frequently utilized gabapentinoid in the treatment of neuropathic pain, but its effectiveness for treating hiccups during the perioperative period has not been well established. We present a patient with a 7-year history of intractable hiccups resistant to chlorpromazine, baclofen, gabapentin, and cervical epidural injections presenting for orthopedic surgery. Perioperative and postoperative pregabalin administration significantly reduced the frequency and severity of hiccups. This case demonstrates the potential for pregabalin in the management of refractory hiccups.

Indexed as

hiccup treatmentintractable hiccupspersistent hiccupssingultus

Identifiers

PMID42436812
PMCPMC13355156

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.