ArticleTranslational andrology and urology2026
MAG-EX study protocol: magnetic stent versus stent on extraction string in patients after ureteroscopy-a multi-centre randomised controlled trial.
Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Post-operative ureteric stents are commonly utilised after endoscopic intervention for urolithiasis to maintain ureteric patency due to the risks of post-operative ureteric obstruction from stone fragments, oedema or trauma from instrumentation. Unintended premature dislodgement and need for cystoscopic removal pose significant clinical and economic burden to the health care system. Alternative stents such as magnetic stents and stents on extraction strings (SOES) aim to reduce the need for removal under cystoscopy. There is a paucity of data in comparing these alternative stents directly to help guide which stent is more suitable for usage in post-ureteroscopy patients with urolithiasis. Methods: MAG-EX is a prospective, multicentre, randomised clinical trial conducted in two tertiary centres in Sydney, Australia. A total of 276 participants (138 per group) will be enrolled to detect an 8% difference in complication rates with 80% power and a significance level of 0.05. Adult patients undergoing ureteroscopy for unilateral stone disease will be randomised to receive either SOES or magnetic stents. The primary outcome is the rate of premature stent removal or requirement for cystoscopic removal within one week. Secondary outcomes include patient-reported measures such as Ureteral Stent Symptom Questionnaire (USSQ), Visual Analogue Scale (VAS), and Patient Reported Outcome Measures (PROMs), as well as patient satisfaction and cost analysis. Follow-up will occur at stent removal and at 30 days post-insertion. Data will be collected using Research Electronic Data Capture (REDCap) and analysed in a blinded manner. Discussion: This trial aims to determine if magnetic stents or SOES are more reliable in preventing premature stent removal and removal requiring cystoscopy. The MAG-EX trial will measure and compare the rates of premature ureteric stent removal and removal of ureteric stents under cystoscopy between stents on extraction string and magnetic stents. A comparison of costs and patient reported outcomes between the two types of stents will be used to inform clinicians, patients and health care providers. This will establish which alternative ureteric stent is more suitable for usage in post-ureteroscopy patients with urolithiasis. Trial Registration: Australian New Zealand Clinical Trials Registry: ACTRN12624000215527.
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