Evidence map›Paper›PMID 42436709›Full record

ArticleNAM journal2026

Advancing next-generation risk assessment for cosmetic ingredients: transferring the 10-step read-across framework from human to environmental safety using triclosan as a case study.

Harald Streicher, Sanghamitra Mishra, Zakaria Naddi, Rita Fernandes, Monica Autiero, Sophia Krause, Avneet Kaur Suri, Celine De Roy, Andreas Schepky, Abdulkarim Najjar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NAM journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Harald StreicherBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.
Sanghamitra MishraToxMinds BV, Brussels, Belgium.
Zakaria NaddiBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.
Rita FernandesBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.
Monica AutieroToxMinds BV, Brussels, Belgium.
Sophia KrauseBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.
Avneet Kaur SuriToxMinds BV, Brussels, Belgium.
Celine De RoyToxMinds BV, Brussels, Belgium.
Andreas SchepkyBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.
Abdulkarim NajjarBeiersdorf AG, Beiersdorfstrasse 1-9, 22529, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental risk assessment (ERA) has not yet undergone the shift toward new approach methodologies (NAMs), that has reshaped human health safety assessment. This study adapts the 10-step read across next generation risk assessment (NGRA) framework developed for cosmetic safety, to the environmental domain and applies it to triclosan (TCS), given its data richness and environmental relevance. The framework consists of three tiers: Tier 0 for problem formulation and

Indexed as

CosmeticsEnvironmental risk assessmentIn vitro to in vivo extrapolationNew approach methodologiesNext-generation risk assessmentPersonal care productsRead-acrossTriclosan

Identifiers

PMID42436709
PMCPMC13355825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.