Evidence map›Paper›PMID 42436603›Full record

ArticleNeonatology2026

Postnatal Changes in Fetal Hemoglobin and Tissue Oxygenation in Preterm and Term Neonates: A Prospective Observational Study.

Ena Suppan, Thomas Suppan, Bernhard Schwaberger, Christina H Wolfsberger, Nariae Baik-Schneditz, Daniel Pfurtscheller, Christoph Schlatzer, Melina Winkler, Gerhard Pichler

Abstract read
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In one paragraph

Article in Neonatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ena SuppanDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria, ena.suppan@medunigraz.at.
Thomas SuppanDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Bernhard SchwabergerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Christina H WolfsbergerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Nariae Baik-SchneditzDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Daniel PfurtschellerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Christoph SchlatzerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Melina WinklerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
Gerhard PichlerDivision of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhysiological postnatal changes in fetal hemoglobin fraction (FHbF) may affect neonatal tissue oxygenation through shifts in the oxyhemoglobin dissociation curve. We examined cross-sectional associations between FHbF and near-infrared spectroscopy (NIRS)-derived tissue oxygenation, and longitudinal associations between within-infant changes in FHbF and cerebral tissue oxygenation (cStO

methodsThis prospective observational study included 25 preterm (median [IQR] gestational age 33.6 [1.6] weeks) and 25 term (39.9 [1.4] weeks) neonates in a tertiary-center neonatal unit. Measurements were performed at T1 (days 2-3), T2 (days 5-10), and T3 (days 12-18). cStO

resultsNo significant cross-sectional correlations were identified between FHbF and cerebral or peripheral NIRS-derived variables at any time point. Over time, Hb and cStO

conclusionWithin-infant FHbF decline was associated with increased cStO

Indexed as

Fetal hemoglobinNear-infrared spectroscopyNeonateTissue oxygenation

Identifiers

PMID42436603
PMCPMC13480971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.