Evidence map›Paper›PMID 42436587›Full record

ArticleJournal of neuroengineering and rehabilitation2026

Technology-enabled telerehabilitation for Parkinson's disease: a scoping review of digital rehabilitation systems, delivery architectures, and implementation challenges.

Chiara Longo, Lorenzo Gios, Susanna Pardini, Raffaello Ferrari, Anita Daves, Giuseppe Jurman, Maria Chiara Malaguti

Abstract readScoping Review
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chiara LongoAzienda Sanitaria Universitaria Integrata del Trentino (ASUIT) di Trento, Trento, Italy.ORCID http://orcid.org/0000-0001-6904-6494
Lorenzo GiosDigital Health & Wellbeing Center, Fondazione Bruno Kessler, Via Sommarive, 18, Trento, 38123, Italy. lgios@fbk.eu.ORCID http://orcid.org/0000-0003-2981-0851
Susanna PardiniDigital Health Research Unit, Digital Health & Wellbeing Center, Fondazione Bruno Kessler, Via Sommarive, 18, Trento, 38123, Italy.ORCID http://orcid.org/0000-0002-6692-8923
Raffaello FerrariAzienda Sanitaria Universitaria Integrata del Trentino (ASUIT) di Trento, Trento, Italy.
Anita DavesAzienda Sanitaria Universitaria Integrata del Trentino (ASUIT) di Trento, Trento, Italy.ORCID http://orcid.org/0009-0006-6081-5975
Giuseppe JurmanDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20072, MI, Italy.ORCID http://orcid.org/0000-0002-2705-5728
Maria Chiara MalagutiAzienda Sanitaria Universitaria Integrata del Trentino (ASUIT) di Trento, Trento, Italy.ORCID http://orcid.org/0000-0002-4807-4063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDigital technologies are increasingly integrated into neurorehabilitation programs for Parkinson's Disease (PD), enabling remote delivery of therapy, continuous monitoring of motor performance, and adaptive feedback during rehabilitation training. Telerehabilitation systems incorporating wearable sensors, virtual reality platforms, mobile applications, and artificial intelligence (AI) have expanded rapidly in recent years. However, the evidence base remains fragmented across heterogeneous technological configurations, clinical contexts, and delivery models, limiting a comprehensive understanding of how digital rehabilitation systems are implemented in PD care.

methodsThis scoping review maps the current literature on telerehabilitation for PD with a focus on the technological architectures, care settings, and delivery models used in digital rehabilitation programs. Peer-reviewed studies published between 2020 and 2025 were identified through searches in PubMed with reference to Scopus and Web of Science. Eligible studies investigated remote rehabilitation interventions for PD using digital technologies such as wearable sensors, mobile health applications, virtual reality systems, and AI-supported monitoring tools. Evidence was analyzed across three domains: (i) technological components and digital rehabilitation systems, (ii) rehabilitation setting, and (iii) delivery model.

resultsFifty-three studies met the inclusion criteria. Most interventions were home-based and implemented multi-component digital architectures combining teleconferencing platforms, wearable sensors, and mobile applications. Wearable sensing technologies were used in nearly half of the studies to quantify gait, balance, or tremor, while video platforms and mobile applications supported remote supervision and exercise delivery. Virtual reality systems and serious games were used to enhance engagement and taskspecific training, whereas AI techniques were increasingly integrated to support movement detection, monitoring, and adaptive feedback. Despite generally high usability and acceptability, substantial heterogeneity was observed in outcome measures, terminology, and safety reporting. Few studies explicitly described care pathways, delivery architectures, or long-term clinical outcomes. DISSCUSSION: Telerehabilitation for Parkinson's disease is evolving toward integrated digital rehabilitation ecosystems combining wearable sensing, software platforms, and AI-enabled monitoring. Although feasibility and patient acceptance are consistently reported, current evidence remains limited by heterogeneous reporting standards and insufficient integration between technological systems and clinical workflows. Future research should focus on standardized outcome frameworks, scalable hybrid care models, and the development of interoperable, explainable digital rehabilitation systems capable of supporting long-term neurorehabilitation in real-world settings.

Indexed as

Neurological RehabilitationParkinson DiseaseTelerehabilitationArtificial IntelligenceDigital HealthHumansVirtual RealityWearable Electronic DevicesArtificial intelligenceDigital rehabilitationNeurorehabilitationParkinson’s diseaseRemote monitoringTelerehabilitationVirtual realityWearable sensors

Identifiers

PMID42436587
PMCPMC13644115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.