Evidence map›Paper›PMID 42436527›Full record

ArticleItalian journal of pediatrics2026

Occurrence of diarrhea in pediatric bronchopneumonia patients: relevance to nursing management.

Yinyan Tang, Qian Zhang, Tingting Yu

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Article in Italian journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yinyan Tang *Department of pediatrics, Nanjing Lishui People's Hospital, No. 86 Chongwen Road, Lishui District, Nanjing, Jiangsu Province, China.
Qian Zhang *Department of pediatrics, Nanjing Lishui People's Hospital, No. 86 Chongwen Road, Lishui District, Nanjing, Jiangsu Province, China.
Tingting YuDepartment of pediatrics, Nanjing Lishui People's Hospital, No. 86 Chongwen Road, Lishui District, Nanjing, Jiangsu Province, China. 564440307@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiarrhea represents a frequent complication in pediatric patients with bronchopneumonia. This study was designed to identify independent risk factors for diarrheal complications and to propose evidence-informed nursing interventions.

methodsA retrospective cohort study was conducted among 280 hospitalized children with bronchopneumonia. Demographic, anthropometric, laboratory, and treatment-related data were extracted from electronic medical records. Multicollinearity was assessed by variance inflation factor (VIF), and independent risk factors were identified through binary logistic regression with model fit evaluated by the Hosmer-Lemeshow test.

resultsThe incidence of diarrhea was 23.57%. Eight independent risk factors were identified: antibiotic duration ≥ 7 days (OR = 3.006), β-lactamase inhibitor combination use (OR = 2.916), combined antibiotic use (OR = 2.401), mixed pulmonary infection (OR = 2.105), age < 5 years (OR = 2.048), weight-for-height/length z-score < - 2 (OR = 1.982), serum albumin < 35 g/L (OR = 1.896), and C-reactive protein ≥ 20 mg/L (OR = 1.845). Probiotic administration was an independent protective factor (OR = 0.849). All VIF values were < 5, and the Hosmer-Lemeshow test indicated adequate model fit (P > 0.05).

conclusionDiarrhea in children with bronchopneumonia is associated with multiple clinical and therapeutic variables, with β-lactamase inhibitor combinations and prolonged antibiotic therapy conferring the highest risk. These findings provide a hypothesis-generating foundation for risk-stratified nursing strategies to reduce diarrheal complications. However, given the retrospective design and the inability to distinguish antibiotic-associated diarrhea from infectious diarrhea, the identified associations should be interpreted cautiously, and any derived clinical recommendations require prospective validation.

Indexed as

BronchopneumoniaDiarrheaAnti-Bacterial AgentsChildChild, PreschoolFemaleHumansIncidenceInfantMaleRetrospective StudiesRisk FactorsAnti-Bacterial AgentsBronchopneumoniaChildrenClinicalDiarrheaNursingTreatment

Identifiers

PMID42436527
PMCPMC13644138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.