Evidence map›Paper›PMID 42436520›Full record

ArticleCell communication and signaling : CCS2026

Crosstalk of noradrenergic Ca

Jessica Sauer, Antonia Beiersdorfer, Franz Lennart Schmidt, Mathias Nordbeck, Oana Constantin, Daniela Hirnet, Christine E Gee, Christian Lohr

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell communication and signaling : CCS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jessica SauerDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0009-0006-1954-1175
Antonia BeiersdorferDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0000-0003-0976-005X
Franz Lennart SchmidtDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.
Mathias NordbeckDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0009-0003-0392-6685
Oana ConstantinInstitute of Synaptic Neuroscience, ZMNH, University Medical Center Hamburg- Eppendorf, Hamburg, Germany.ORCID 0000-0002-9238-7139
Daniela HirnetDivision of Neurophysiology, University of Hamburg, Hamburg, Germany.ORCID 0009-0004-0566-4604
Christine E GeeInstitute of Synaptic Neuroscience, ZMNH, University Medical Center Hamburg- Eppendorf, Hamburg, Germany.ORCID 0000-0003-0345-3665
Christian LohrDivision of Neurophysiology, University of Hamburg, Hamburg, Germany. christian.lohr@uni-hamburg.de.ORCID 0000-0001-6518-6422

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic adenosine monophosphate (cAMP) and Ca²⁺ are ubiquitous second messengers that regulate gene expression, metabolism, and synaptic plasticity. Here, we identified a complex interplay between Ca²⁺ and cAMP signaling pathways in mouse olfactory bulb astrocytes. Norepinephrine (NE) elevated both Ca²⁺ and cAMP levels via α

Indexed as

AstrocytesCalciumCalcium SignalingCyclic AMPNorepinephrineOlfactory BulbAdenylyl CyclasesAnimalsCells, CulturedMicePhenylephrineReceptors, Adrenergic, alpha-1Receptors, Adrenergic, alpha-2Signal TransductionAdenylyl CyclasesCalciumCyclic AMPNorepinephrinePhenylephrineReceptors, Adrenergic, alpha-1Receptors, Adrenergic, alpha-2Adenylyl cyclaseastrocytesCa2+Cyclic adenosine monophosphateNorepinephrinePhenylephrine

Identifiers

PMID42436520
PMCPMC13355343

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.