ArticleBMC ophthalmology2026
Multimodal imaging application of Sturge-Weber syndrome complicated with glaucoma: a case report of non-surgical treatment in a 7-year-old boy.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo report the multimodal imaging characteristics and successful non-surgical intraocular pressure (IOP) control with bimatoprost in a 7-year-old boy with Sturge-Weber syndrome (SWS)-related glaucoma and diffuse choroidal hemangioma (DCH).
methodCase report with multimodal imaging including ultra-widefield fluorescein angiography, indocyanine green angiography, B-scan ultrasound, ultrasound biomicroscopy (UBM), and cranial MRI.
resultsA 7-year-old boy with facial port-wine stain (V1 distribution) presented with right ocular distension and IOP of 36 mmHg. Multimodal imaging confirmed DCH, exudative retinal detachment, and open angle. Initial triple therapy (brinzolamide, brimonidine, carteolol) failed to lower IOP. After switching to bimatoprost monotherapy (once daily), IOP decreased to 18 mmHg within 4 weeks and remained stable at 3-month follow-up. No surgical intervention was required.
conclusionIn selected pediatric SWS patients with refractory glaucoma, bimatoprost may achieve excellent IOP control, avoiding surgical risks. Multimodal imaging is essential for accurate diagnosis and monitoring. This case challenges the traditional view that topical medications are ineffective in SWS-related glaucoma and highlights the potential of prostaglandin analogs as a first-line or early adjunctive therapy.
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